ChemicalBook > Product Catalog >Analytical Chemistry >Standard >Pharmaceutical Impurity Reference Standards >(2R,3R,4R,5S,6S)-2-(acetoxymethyl)-6-(4-chloro-3-(4- hydroxybenzyl)phenyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate

(2R,3R,4R,5S,6S)-2-(acetoxymethyl)-6-(4-chloro-3-(4- hydroxybenzyl)phenyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate

(2R,3R,4R,5S,6S)-2-(acetoxymethyl)-6-(4-chloro-3-(4- hydroxybenzyl)phenyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate Structure
CAS No.
1079083-63-8
Chemical Name:
(2R,3R,4R,5S,6S)-2-(acetoxymethyl)-6-(4-chloro-3-(4- hydroxybenzyl)phenyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate
Synonyms
Dapagliflozin-21;Dapagliflozin Impurity 126;Dapagliflozin Impurity 103;Empagliflozin Tetraacetate;Empagliflozin Acetyl impurity;Des(tetrahydrofuran) Empagliflozin Tetraacetate;D-Glucitol, 1,5-anhydro-1-C-[4-chloro-3-[(4-hydroxyphenyl)methyl]phenyl]-, 2,3,4,6-tetraacetate, (1S)-;(2R,3R,4R,5S,6S)-2-(acetoxymethyl)-6-(4-chloro-3-(4-hydroxybenzyl)phenyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate;Empagliflozin impurity 32/Empagliflozin Acetyl impurity/(2R,3R,4R,5S,6S)-2-(acetoxymethyl)-6-(4-chloro-3-(4-hydroxybenzyl)phenyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate
CBNumber:
CB04843939
Molecular Formula:
C27H29ClO10
Molecular Weight:
548.97
MOL File:
1079083-63-8.mol
Modify Date:
2023/4/23 13:52:06

(2R,3R,4R,5S,6S)-2-(acetoxymethyl)-6-(4-chloro-3-(4- hydroxybenzyl)phenyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate Properties

Melting point 149-151°C
storage temp. -20°C Freezer, Under inert atmosphere
solubility DMSO (Slightly), Methanol (Slightly, Sonicated)
form Solid
color White to Off-White

(2R,3R,4R,5S,6S)-2-(acetoxymethyl)-6-(4-chloro-3-(4- hydroxybenzyl)phenyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate Chemical Properties,Uses,Production

Uses

Empagliflozin Tetraacetate is an Empagliflozin (E521510) impurity and is a reagent used to design and synthesize nitric oxide releasing derivatives of dapagliflozin which has potential antidiabetic and antithrombotic agents.

(2R,3R,4R,5S,6S)-2-(acetoxymethyl)-6-(4-chloro-3-(4- hydroxybenzyl)phenyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate Preparation Products And Raw materials

Raw materials

Preparation Products

(2R,3R,4R,5S,6S)-2-(acetoxymethyl)-6-(4-chloro-3-(4- hydroxybenzyl)phenyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate Suppliers

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Dapagliflozin-21 Empagliflozin Acetyl impurity Empagliflozin impurity 32/Empagliflozin Acetyl impurity/(2R,3R,4R,5S,6S)-2-(acetoxymethyl)-6-(4-chloro-3-(4-hydroxybenzyl)phenyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate Empagliflozin Tetraacetate D-Glucitol, 1,5-anhydro-1-C-[4-chloro-3-[(4-hydroxyphenyl)methyl]phenyl]-, 2,3,4,6-tetraacetate, (1S)- Dapagliflozin Impurity 103 Des(tetrahydrofuran) Empagliflozin Tetraacetate (2R,3R,4R,5S,6S)-2-(acetoxymethyl)-6-(4-chloro-3-(4-hydroxybenzyl)phenyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate Dapagliflozin Impurity 126 1079083-63-8