2-(1,5-DIMETHYL-3-OXO-2-PHENYL-2,3-DIHYDRO-1H-PYRAZOL-4-YL)-1,3-DIOXOISOINDOLINE-5-CARBOXYLIC ACID
- CAS No.
- 292870-53-2
- Chemical Name:
- 2-(1,5-DIMETHYL-3-OXO-2-PHENYL-2,3-DIHYDRO-1H-PYRAZOL-4-YL)-1,3-DIOXOISOINDOLINE-5-CARBOXYLIC ACID
- Synonyms
- BV02;TOSLAB 796846;BV02 >=98% (HPLC);BV02, 10 mM in DMSO;2-(1,5-Dimethyl-3-oxo-2-phenylpyrazol-4-yl)-1,3-dioxoisoindole-5-carboxylic acid;2-(1,5-DIMETHYL-3-OXO-2-PHENYL-2,3-DIHYDRO-1H-PYRAZOL-4-YL)-1,3-DIOXOISOINDOLINE-5-CARBOXYLIC ACID;2-(2,3-Dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)-2,3-dihydro-1,3-dioxo-1H-isoindole-5-carboxylic acid;2-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-1,3-dioxo-2,3-dihydro-1H-isoindole-5-carboxylic acid;1H-Isoindole-5-carboxylic acid, 2-(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)-2,3-dihydro-1,3-dioxo-
- CBNumber:
- CB0712242
- Molecular Formula:
- C20H15N3O5
- Molecular Weight:
- 377.35
- MOL File:
- Mol file
- MSDS File:
- SDS
- Modify Date:
- 2025/4/17 18:22:24
2-(1,5-DIMETHYL-3-OXO-2-PHENYL-2,3-DIHYDRO-1H-PYRAZOL-4-YL)-1,3-DIOXOISOINDOLINE-5-CARBOXYLIC ACID price More Price(2)
2-(1,5-DIMETHYL-3-OXO-2-PHENYL-2,3-DIHYDRO-1H-PYRAZOL-4-YL)-1,3-DIOXOISOINDOLINE-5-CARBOXYLIC ACID Chemical Properties,Uses,Production
Uses
BV02 has been used to study the effects of 14-3-3σ on P-glycoprotein and pregnane X receptor protein xpression. It has also been used as a control in studying BAP1 (BRCA1 (breast cancer gene)-associated protein 1) inducing cell death via interaction with 14-3-3 in neuroblastoma.
Biochem/physiol Actions
BV02 is an inhibitor of the 14-3-3 scaffolding proteins docking site. BV02 promotes the apoptotic death of cells expressing either wt Bcr-Abl construct or T315I mutation. It induces apoptosis by c-Abl release from 14-3-3? and re-location to nuclear compartment and at mitochondrial membranes.
2-(1,5-DIMETHYL-3-OXO-2-PHENYL-2,3-DIHYDRO-1H-PYRAZOL-4-YL)-1,3-DIOXOISOINDOLINE-5-CARBOXYLIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
2-(1,5-DIMETHYL-3-OXO-2-PHENYL-2,3-DIHYDRO-1H-PYRAZOL-4-YL)-1,3-DIOXOISOINDOLINE-5-CARBOXYLIC ACID Suppliers
Global( 23)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 32251 | 58 | Inquiry |
| Aladdin Scientific | United States | 52924 | 58 | Inquiry | |
| RD International Technology Co., Limited | 18024082417 | China | 9835 | 58 | Inquiry |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | China | 9803 | 58 | Inquiry |
| TargetMol Chemicals Inc. | 4008200310 | China | 24762 | 58 | Inquiry |
| Bide Pharmatech Ltd. | 400-1647117 13681763483 | China | 62072 | 58 | Inquiry |
| Proteintech China | 027-87531629 | CHINA | 6290 | 58 | Inquiry |
| Sangon Biotech (Shanghai) Co.,Ltd. | 400-821-026 | China | 48813 | 58 | Inquiry |
| Merck KGaA | 21-20338288 | China | 292394 | 58 | Inquiry |
| Absin Bioscience Inc. | 021-38015121-8802 | CHINA | 6208 | 58 | Inquiry |
2-(1,5-DIMETHYL-3-OXO-2-PHENYL-2,3-DIHYDRO-1H-PYRAZOL-4-YL)-1,3-DIOXOISOINDOLINE-5-CARBOXYLIC ACID Spectrum
TOSLAB 796846
2-(1,5-DIMETHYL-3-OXO-2-PHENYL-2,3-DIHYDRO-1H-PYRAZOL-4-YL)-1,3-DIOXOISOINDOLINE-5-CARBOXYLIC ACID
2-(2,3-Dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)-2,3-dihydro-1,3-dioxo-1H-isoindole-5-carboxylic acid
BV02
2-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-1,3-dioxo-2,3-dihydro-1H-isoindole-5-carboxylic acid
BV02 >=98% (HPLC)
1H-Isoindole-5-carboxylic acid, 2-(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)-2,3-dihydro-1,3-dioxo-
BV02, 10 mM in DMSO
2-(1,5-Dimethyl-3-oxo-2-phenylpyrazol-4-yl)-1,3-dioxoisoindole-5-carboxylic acid
292870-53-2