α-Amanitin

α-Amanitin Structure
CAS No.
11030-71-0
Chemical Name:
α-Amanitin
Synonyms
α-Amanitin
CBNumber:
CB0944238
Molecular Formula:
C39H53N9O14S
Molecular Weight:
903.95502
MOL File:
11030-71-0.mol
Modify Date:
2022/12/21 16:56:50

α-Amanitin Properties

Melting point 245 °C (decomp)

SAFETY

Risk and Safety Statements

Toxicity A drug derived from the highly poisonous fungus Amanita phalloides (death cap). Alpha-amanitin, a cyclic octapeptide, is toxic because of its affinity for RNA polymerase II in eukaryotic cells. Since this enzyme is responsible for mRNA synthesis in the cell, the compound is a potent and selective inhibitor of mRNA synthesis. It is effective at concentrations below 1 μg/mL, and its specific action has made it useful in experimental biology. It is often used with actinomycin D to block RNA synthesis.

α-Amanitin Preparation Products And Raw materials

Raw materials

Preparation Products

α-Amanitin 11030-71-0 C39H54N10O13S