8,11-dihydroxy-4-(2-hydroxyethyl)-6-((2-((2-hydroxyethyl)amino)ethyl)amino)-1,2,3,4,7,12-hexahydronaphtho(2,3-f)quinoxaline-7,12-dione

8,11-dihydroxy-4-(2-hydroxyethyl)-6-((2-((2-hydroxyethyl)amino)ethyl)amino)-1,2,3,4,7,12-hexahydronaphtho(2,3-f)quinoxaline-7,12-dione Structure
CAS No.
137132-70-8
Chemical Name:
8,11-dihydroxy-4-(2-hydroxyethyl)-6-((2-((2-hydroxyethyl)amino)ethyl)amino)-1,2,3,4,7,12-hexahydronaphtho(2,3-f)quinoxaline-7,12-dione
Synonyms
Mitoxantrone IMpurity D;Mitoxantrone EP Impurity D;Mitoxantrone EP Impurity D HCl;Mitoxantrone (2-Hydroxyethyl)piperazine Impurity;Mitoxantrone Impurity 4(Mitoxantrone EP Impurity A);Mitoxantrone Impurity 4(Mitoxantrone EP Impurity D);Mitoxantrone (2-Hydroxyethyl)piperazine IMpurity (Mitoxantrone IMpurity D);8,11-Dihydroxy-4-(2-hydroxyethyl)-6-(2-(2-hydroxyethylamino)ethylamino)-1,2,3,4-tetrahydronaph;1,2,3,4-Tetrahydro-8,11-dihydroxy-4-(2-hydroxyethyl)-6-[[2-[(2-hydroxyethyl)aMino]ethyl]aMino]naphtho[2,3-f]quinoxaline-7,12-dione;Naphtho[2,3-f]quinoxaline-7,12-dione, 1,2,3,4-tetrahydro-8,11-dihydroxy-4-(2-hydroxyethyl)-6-[[2-[(2-hydroxyethyl)amino]ethyl]amino]-
CBNumber:
CB11346922
Molecular Formula:
C22H26N4O6
Molecular Weight:
442.46
MOL File:
137132-70-8.mol
Modify Date:
2023/4/23 13:52:06

8,11-dihydroxy-4-(2-hydroxyethyl)-6-((2-((2-hydroxyethyl)amino)ethyl)amino)-1,2,3,4,7,12-hexahydronaphtho(2,3-f)quinoxaline-7,12-dione Properties

Melting point 175-179°C
Boiling point 843.2±65.0 °C(Predicted)
Density 1.473±0.06 g/cm3(Predicted)
storage temp. Refrigerator
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
pka 7.45±0.20(Predicted)
color Dark Blue to Black

8,11-dihydroxy-4-(2-hydroxyethyl)-6-((2-((2-hydroxyethyl)amino)ethyl)amino)-1,2,3,4,7,12-hexahydronaphtho(2,3-f)quinoxaline-7,12-dione Chemical Properties,Uses,Production

Chemical Properties

Dark Blue Solid

Uses

A metabolite of the anticancer agent Mitoxantrone (M373425)

8,11-dihydroxy-4-(2-hydroxyethyl)-6-((2-((2-hydroxyethyl)amino)ethyl)amino)-1,2,3,4,7,12-hexahydronaphtho(2,3-f)quinoxaline-7,12-dione Preparation Products And Raw materials

Raw materials

Preparation Products

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137132-70-8(8,11-dihydroxy-4-(2-hydroxyethyl)-6-((2-((2-hydroxyethyl)amino)ethyl)amino)-1,2,3,4,7,12-hexahydronaphtho(2,3-f)quinoxaline-7,12-dione)Related Search:

1,2,3,4-Tetrahydro-8,11-dihydroxy-4-(2-hydroxyethyl)-6-[[2-[(2-hydroxyethyl)aMino]ethyl]aMino]naphtho[2,3-f]quinoxaline-7,12-dione Mitoxantrone IMpurity D 8,11-Dihydroxy-4-(2-hydroxyethyl)-6-(2-(2-hydroxyethylamino)ethylamino)-1,2,3,4-tetrahydronaph Mitoxantrone Impurity 4(Mitoxantrone EP Impurity A) 8,11-dihydroxy-4-(2-hydroxyethyl)-6-((2-((2-hydroxyethyl)amino)ethyl)amino)-1,2,3,4,7,12-hexahydronaphtho(2,3-f)quinoxaline-7,12-dione Mitoxantrone (2-Hydroxyethyl)piperazine IMpurity (Mitoxantrone IMpurity D) Mitoxantrone EP Impurity D HCl Mitoxantrone (2-Hydroxyethyl)piperazine Impurity Mitoxantrone Impurity 4(Mitoxantrone EP Impurity D) Mitoxantrone EP Impurity D Naphtho[2,3-f]quinoxaline-7,12-dione, 1,2,3,4-tetrahydro-8,11-dihydroxy-4-(2-hydroxyethyl)-6-[[2-[(2-hydroxyethyl)amino]ethyl]amino]- 137132-70-8 19741-14-7 Amines Aromatics Heterocycles Intermediates & Fine Chemicals Metabolites & Impurities Pharmaceuticals