15-hexadecynoic acid

15-hexadecynoic acid Structure
CAS No.
99208-90-9
Chemical Name:
15-hexadecynoic acid
Synonyms
Boc-β-homoarginine;Alkyne-palmitic acid;Palmitic Acid Alkyne;15-hexadecynoic acid;hexadec-15-ynoic acid;Alkynyl Palmitic Acid;Palmitic acid (15-yne);15-hexadecyn-1-oic acid;15-HEXADECYNOIC ACID;PALMITIC ACID (15-YNE);inhibit,PROTAC Linkers,Alk-C16,Inhibitor,Alkynyl Palmitic Acid
CBNumber:
CB11373586
Molecular Formula:
C16H28O2
Molecular Weight:
252.39
MOL File:
99208-90-9.mol
MSDS File:
SDS
Modify Date:
2024/7/2 8:54:59

15-hexadecynoic acid Properties

Melting point 59.1°C (estimate)
Boiling point 409.64°C (rough estimate)
Density 0.9310 (rough estimate)
refractive index 1.4217 (estimate)
storage temp. -20°C
solubility DMF: 30 mg/ml; DMSO: 20 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS(pH 7.2) (1:5): 0.15 mg/ml
form A crystalline solid
color White to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338

15-hexadecynoic acid Chemical Properties,Uses,Production

Uses

15-hexadecynoic acid is a form of palmitic acid with an ω-terminal alkyne. The terminal alkyne group can be used in linking reactions, known as click chemistry; this chemistry is characterized by high dependability and specificity of the azide-alkyne bioconjugation reactions. The use of palmitic acid alkyne and related lipids in isolating palmitoylated proteins has been described.

Biochem/physiol Actions

Alkynyl palmitic acid (aPA) is a modified palmitic acid with an ω-terminal alkyne. The terminal alkyne group can be used in a highly specific linking reaction with azide-containing reagents, known as ‘click chemistry′. The click chemistry reactions are rapid, convenient, versatile and regiospecific. They are easy to purify. aPA can be used for isolating palmitoylated proteins.

15-hexadecynoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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15-hexadecynoic acid Palmitic Acid Alkyne hexadec-15-ynoic acid 15-HEXADECYNOIC ACID;PALMITIC ACID (15-YNE) Palmitic acid (15-yne) Alkynyl Palmitic Acid Boc-β-homoarginine 15-hexadecyn-1-oic acid inhibit,PROTAC Linkers,Alk-C16,Inhibitor,Alkynyl Palmitic Acid Alkyne-palmitic acid 99208-90-9