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Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate

Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate Structure
CAS No.
184177-81-9
Chemical Name:
Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate
Synonyms
Posaconazole SM2;Posaconazole Impurity 14;Posaconazole Impurity 56;Intermediate of Posaconazole;Phenyl (4-(4-(4-hydroxyphenyl);piperazin-1-yl)phenylcarbamate;Posaconazole Hydroxy Carbamate Impurity;Posaconazole Diastereoisomer 3 (S,R,R,R);4-(4-(4-HYDROXYPHENYL)PIPERAZIN-1-YL)PHENYL CARBAMATE;PHENYL {4-[4-(4-HYDROXYPHENYL)PIPERAZIN-1-YL]PHENYL}CARBAMATE
CBNumber:
CB11476162
Molecular Formula:
C23H23N3O3
Molecular Weight:
389.45
MOL File:
184177-81-9.mol
MSDS File:
SDS
Modify Date:
2024/6/28 14:37:56
Request For Quotation

Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate Properties

Boiling point 603.9±55.0 °C(Predicted)
Density 1.296
storage temp. Sealed in dry,Room Temperature
pka 12.18±0.30(Predicted)
InChI InChI=1S/C23H23N3O3/c27-21-12-10-20(11-13-21)26-16-14-25(15-17-26)19-8-6-18(7-9-19)24-23(28)29-22-4-2-1-3-5-22/h1-13,27H,14-17H2,(H,24,28)
InChIKey IKRKMYDCUZYKHX-UHFFFAOYSA-N
SMILES C(OC1=CC=CC=C1)(=O)NC1=CC=C(N2CCN(C3=CC=C(O)C=C3)CC2)C=C1
CAS DataBase Reference 184177-81-9

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS09
Signal word  Warning
Hazard statements  H410
Precautionary statements  P273-P391-P501

Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate Chemical Properties,Uses,Production

Description

Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate is a piperazine derivative that inhibits the growth of gram-positive bacteria.Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate is a carbamic acid that binds to the 50S ribosomal subunit of bacteria, preventing transcription and replication. Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)) carbamate is a carbamic acid that binds to the 50S ribosomal subunit of bacteria, preventing transcription and replication. Human activity on human erythrocytes using the membrane clamp technique is frequent. This active form is metabolised by a number of metabolic transformations including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or binding to glucuronic acid.

Uses

PHENYL {4-[4-(4-HYDROXYPHENYL)PIPERAZIN-1-YL]PHENYL}CARBAMATE is a carboxylic acid ester organic substance and can be used as a pharmaceutical intermediate.

Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate Preparation Products And Raw materials

Raw materials

1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine Phenyl chloroformate

Preparation Products

2,4-DIHYDRO-4-[(4-(4-HYDROXYPHENYL)-1-PIPERAZINYL)PHENYL]-2-(1-METHYLPROPYL)-3H-1,2,4-TRIAZOLE-3-ONE 2-[(1S,2S)-1-ethyl-2-bezyloxypropyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]- 3H-1,2,4-Triazol-3-one,

Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate Suppliers

Global( 194)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Urantiis Pharmaceuticals Private Limited +918790703567 AndhraPradesh, India 80 58 Inquiry
Rampex Labs Private Limited +91 9168074433 Telangana, India 71 58 Inquiry
VGS SYNTHESIS PRIVATE LIMITED +91-9866975588 +91-9866975588 Hyderabad, India 1818 58 Inquiry
Sridhara Laboratories Pvt Ltd +91-8008320202 +91-9396166660 Telangana, India 26 58 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
SynZeal Research Pvt Ltd +1 226-802-2078 Gujarat, India 6522 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
Shaanxi LuyuanBiomedicine Co., LTD +86-13991827389 +86-13991827389 China 51 58 Inquiry
CONIER CHEM AND PHARMA LIMITED +8618523575427 China 49391 58 Inquiry
Supplier Advantage
Urantiis Pharmaceuticals Private Limited 58
Rampex Labs Private Limited 58
VGS SYNTHESIS PRIVATE LIMITED 58
Sridhara Laboratories Pvt Ltd 58
A.J Chemicals 58
CLEARSYNTH LABS LTD. 58
SynZeal Research Pvt Ltd 58
Pharmaffiliates Analytics and Synthetics P. Ltd 58
Shaanxi LuyuanBiomedicine Co., LTD 58
CONIER CHEM AND PHARMA LIMITED 58

184177-81-9(Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate)Related Search:

4-Methoxyphenol Posaconazole Impurity 44 (5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester Posaconazole Impurity 51 D-threo-Pentitol, 2,5-anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-(hydroxyMethyl)-1-(1H-1,2,4-triazol-1-yl)-
4-([4-(4-METHYLOXY-PHENYL)-PIPERAZIN-1-YL]-PHENYL)-CARBAMIC ACID PHENYL ESTER 1-(4-Methoxyphenyl)-4-(4-nitrophenyl)piperazine Posaconazole Impurity 47 Posaconazole Impurity 42 1-(((2R,4R)-4-((Benzyloxy)methyl)-2-(2,4-difluorophenyl)tetrahydrofuran-2-yl)methyl)-1H-1,2,4-triazole
1,3-PROPANEDIOL, 2-[2-(2,4-DIFLUOROPHENYL)-2-PROPEN-1-YL]- 1-(4-Methoxyphenyl)piperazine Posaconazole Impurity 50 Hydrazine, [1-ethyl-2-(phenylmethoxy)propyl]-,[S-(R*,R*)]-(9CI) [(2S,3S)-2-(benzyloxy)pentan-3-yl]hydrazine
2-[(1S,2S)-1-Ethyl-2-(phenylmethoxy)propyl]hydrazinecarboxaldehyde 1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine 4-Chloro-benzenesulfonic acid 5-(2,4-difluoro-phenyl)-5-[1,2,4]triazol-1-ylMethyl-tetrahydro-furan-3-ylMethyl ester
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CarbaMic acid, [4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]-, phenyl ester (9CI) Posaconazole Impurity 14 PHENYL {4-[4-(4-HYDROXYPHENYL)PIPERAZIN-1-YL]PHENYL}CARBAMATE [4-[4-(4-Hydroxyphenyl)-1-piperazinyl]phenyl]carbamic acid phenyl ester Phenyl (4-(4-(4-hydroxyphenyl) phenyl N-[4-[4-(4-hydroxyphenyl)piperazin-1-yl]phenyl]carbamate 4-(4-(4-HYDROXYPHENYL)PIPERAZIN-1-YL)PHENYL CARBAMATE Phenyl {4-[4-(4-Hydroxyphenyl)Piperazin-1-Yl]Phenyl}Carbamat... Posaconazole SM2 Carbamic acid, N-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]-, phenyl ester Posaconazole Hydroxy Carbamate Impurity Posaconazole Impurity 56 piperazin-1-yl)phenylcarbamate Posaconazole Diastereoisomer 3 (S,R,R,R) Intermediate of Posaconazole Phenyl {4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl}carbamate 184177-81-9