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ChemicalBook > Product Catalog >Pharmaceutical intermediates >Heterocyclic compound >Pyrazines >8-Chloro-3-iodoimidazo[1,2-a]pyrazine

8-Chloro-3-iodoimidazo[1,2-a]pyrazine

8-Chloro-3-iodoimidazo[1,2-a]pyrazine Structure
CAS No.
1049677-32-8
Chemical Name:
8-Chloro-3-iodoimidazo[1,2-a]pyrazine
Synonyms
8-Chloro-3-iodoimidazo[1,2-a]pyrazine;Imidazo[1,2-a]pyrazine, 8-chloro-3-iodo-
CBNumber:
CB11482006
Molecular Formula:
C6H3ClIN3
Molecular Weight:
279.47
MOL File:
1049677-32-8.mol
MSDS File:
SDS
Modify Date:
2023/10/16 11:32:06
Request For Quotation

8-Chloro-3-iodoimidazo[1,2-a]pyrazine Properties

Density 2.34

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
HS Code  2933998090

8-Chloro-3-iodoimidazo[1,2-a]pyrazine Chemical Properties,Uses,Production

Chemical Properties

off-white solid

Biological Activity

8-Chloro-3-iodoimidazo[1,2-a]pyrazine has demonstrated broad-spectrum antibacterial activity at low concentration levels against both gram-positive and gram-negative bacteria. Its antimicrobial potency can be increased by structural modifications.

Synthesis

8-chloroimidazo[1,2-a]pyrazine (5.2 g, 33.9 mmol) and N-iodo-succinimide (NIS) (8 g, 35.6 mmol) were combined with DMF (34 ml). The reaction mixture was stirred at RT for 48 h. After that, the water was added to the suspension, and the solid was filtered, washed with water and MeOH, and dried under HV to afford 8-Chloro-3-iodoimidazo[1,2-a]pyrazine (7.17 g, 25.6 mmol, 75.8% yield).
8-Chloro-3-iodoimidazo[1,2-a]pyrazine

8-Chloro-3-iodoimidazo[1,2-a]pyrazine Preparation Products And Raw materials

Raw materials

N-(4-AMINOPHENYL)-2-MORPHOLIN-4-YLACETAMIDE 8-Chloro-imidazo[1,2-a]pyrazine

Preparation Products

8-Chloro-3-iodoimidazo[1,2-a]pyrazine Suppliers

Global( 55)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
Shanghai Boc Chemical Co., Ltd. 021-34975602; +8618721111801 China 138 58 Inquiry
Capot Chemical Co.,Ltd. 571-85586718 +8613336195806 China 29798 60 Inquiry
CONIER CHEM AND PHARMA LIMITED +8618523575427 China 49391 58 Inquiry
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd +8613580539051 CHINA 21149 58 Inquiry
Career Henan Chemica Co +86-0371-86658258 +8613203830695 China 30253 58 Inquiry
Dayang Chem (Hangzhou) Co.,Ltd. 571-88938639 +8617705817739 China 52861 58 Inquiry
PT CHEM GROUP LIMITED +86-85511178 +86-85511178 China 35451 58 Inquiry
GIHI CHEMICALS CO.,LIMITED +8618058761490 China 49999 58 Inquiry
LEAPCHEM CO., LTD. +86-852-30606658 China 43348 58 Inquiry
Supplier Advantage
A.J Chemicals 58
Shanghai Boc Chemical Co., Ltd. 58
Capot Chemical Co.,Ltd. 60
CONIER CHEM AND PHARMA LIMITED 58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd 58
Career Henan Chemica Co 58
Dayang Chem (Hangzhou) Co.,Ltd. 58
PT CHEM GROUP LIMITED 58
GIHI CHEMICALS CO.,LIMITED 58
LEAPCHEM CO., LTD. 58

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8-Chloro-3-iodoimidazo[1,2-a]pyrazine Imidazo[1,2-a]pyrazine, 8-chloro-3-iodo- 1049677-32-8