Ristocetin A sulfate
- CAS No.
- 11140-99-1
- Chemical Name:
- Ristocetin A sulfate
- Synonyms
- RISTON;SPONTIN;RISTOMYCIN;RISTOCETIN A;RISTOCETINSULFATQ;ristomycin,sulfate;RISTOCETIN SULFATE;RISTOCETIN A SULFATE;Ristocetin A sulphate;RISTOMYCIN MONOSULFATE
- CBNumber:
- CB1251133
- Molecular Formula:
- C95H112N8O48S
- Molecular Weight:
- 2166
- MOL File:
- 11140-99-1.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/5/15 10:43:32
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS05 |
---|---|
Signal word | Warning |
Hazard statements | H314 |
Precautionary statements | P264b-P271-P280-P301+P330+P331-P304+P340-P305+P351+P338-P310-P363-P403+P233-P501c |
Hazard Codes | Xi |
Risk Statements | 36/38 |
Safety Statements | 22-24/25-37/39-26 |
RIDADR | 3249 |
WGK Germany | 3 |
RTECS | VJ8650000 |
F | 8-10-23 |
HazardClass | 6.1(b) |
PackingGroup | III |
Toxicity | mouse,LD50,intravenous,660mg/kg (660mg/kg),BEHAVIORAL: TREMORLUNGS, THORAX, OR RESPIRATION: OTHER CHANGESBEHAVIORAL: EXCITEMENT,Antibiotiki i Meditsinskaya Biotekhnologiya. Antibiotics and Medical Biotechnology. Vol. 32, Pg. 910, 1987. |
Ristocetin A sulfate price More Price(2)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | R7752 | Ristomycin monosulfate ≥90% ristocetin?A basis (balance primarily Ristocetin?B) | 11140-99-1 | 100MG | ₹69821.25 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | R7752 | Ristomycin monosulfate ≥90% ristocetin?A basis (balance primarily Ristocetin?B) | 11140-99-1 | 250MG | ₹136395 | 2022-06-14 | Buy |
Ristocetin A sulfate Chemical Properties,Uses,Production
Uses
Ristocetin A sulfate is a potent antibacterial glycopeptide antibiotic that was withdrawn from clinical use following a high incidence of thrombocytopenia. Further investigation found that ristocetin A induced platelet aggregation by binding to a factor absent in people suffering from von Willebrand's disease, leading to the use of ristocetin A as an important diagnostic aid.
General Description
Ristomycin/ristocetin is a type III glycopeptide. It is a highly glycosylated glycopeptide, previously found in?Amycolatopsis lurida.
Biochem/physiol Actions
Ristocetin activates platelets. Ristocetin-induced platelet agglutination (RIPA) is decreased in patients undergoing chronic hemodialysis. Together with increased plasma glycocalicin levels (a product of enzymatic cleavage of GPIb), RIPA may contribute to diminished platelet adhesion to vascular subendothelium and increased bleeding associated with uremia. Addition of ristocetin and vWf caused specific agglutination of rGPIbα-liposomes suporting the potential use of rGPIbα-liposomes to enhance platelet function in vivo and support hemostasis in thrombocytopenic individuals.
Ristocetin A sulfate Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | China | 21663 | 55 | Inquiry |
career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29899 | 58 | Inquiry |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | China | 39916 | 58 | Inquiry |
AFINE CHEMICALS LIMITED | +86-0571-85134551 | China | 15373 | 58 | Inquiry |
BOC Sciences | 16314854226; +16314854226 | United States | 19743 | 58 | Inquiry |
Aladdin Scientific | +1-+1(833)-552-7181 | United States | 57511 | 58 | Inquiry |
Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-400-6206333 18521732826 | China | 25009 | 65 | Inquiry |
RD International Technology Co., Limited | 18024082417 | China | 9268 | 58 | Inquiry |
Nacalai Tesque, Inc. | 81 75 251 1723 | Japan | 6048 | 75 | Inquiry |
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