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2-Bromo-5-ethynylpyridine

2-Bromo-5-ethynylpyridine Structure
CAS No.
569672-28-2
Chemical Name:
2-Bromo-5-ethynylpyridine
Synonyms
2-broMo-5-ethynylpyridine;Pyridine, 2-bromo-5-ethynyl-
CBNumber:
CB12665079
Molecular Formula:
C7H4BrN
Molecular Weight:
182.02
MOL File:
569672-28-2.mol
Modify Date:
2023/11/9 14:34:49

2-Bromo-5-ethynylpyridine Properties

Melting point 83℃
Boiling point 231.0±25.0 °C(Predicted)
Density 1.60±0.1 g/cm3(Predicted)
storage temp. 2-8°C
pka -0.73±0.10(Predicted)
InChI InChI=1S/C7H4BrN/c1-2-6-3-4-7(8)9-5-6/h1,3-5H
InChIKey WRORYOXBXUUDJL-UHFFFAOYSA-N
SMILES C1(Br)=NC=C(C#C)C=C1

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H320-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338

2-Bromo-5-ethynylpyridine Chemical Properties,Uses,Production

Uses

2-Bromo-5-ethynylpyridine is used in the synthesis of macrocycle of terpyridine units.

Preparation

The iodobromopyridine (2-Bromo-5-iodopyridine), the starting material, was coupled with TMS-acetylene under Sonogashira conditions. One-pot deprotection and recrystallization could yield the bromo,ethynyl-functionalized pyridine (2-Bromo-5-ethynylpyridine)[1].
2-Bromo-5-ethynylpyridine

Reactions

2-Bromo-5-ethynylpyridine is a useful organic compound that could be used to synthesize 2-Bromo-5-[(3-iodophenyl)ethynyl]pyridine, 2-bromo-5-({4-[(tert-butyldimethylsilyl)oxy]phenyl}ethynyl)pyridine, and so on.

2-Bromo-5-ethynylpyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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Shanghai Haohong Pharmaceutical Co., Ltd. 400-8210725 4008210725 China 40035 58 Inquiry
2-broMo-5-ethynylpyridine Pyridine, 2-bromo-5-ethynyl- 569672-28-2