(R)-N-(1-Carboxyethyl)-D-norvaline 1-Ethyl Ester

(R)-N-(1-Carboxyethyl)-D-norvaline 1-Ethyl Ester Structure
CAS No.
145682-38-8
Chemical Name:
(R)-N-(1-Carboxyethyl)-D-norvaline 1-Ethyl Ester
Synonyms
Perindopril Impurity 19;Perindopril Impurity 26;Perindopril Related Compound 10;N-[(R)-1-Carbethoxybutyl]-(R)-alanine;((R)-1-Ethoxy-1-oxopentan-2-yl)-D-alanine;(R)-N-(1-Carboxyethyl)-D-norvaline 1-Ethyl Ester;D-Norvaline, N-[(1R)-1-carboxyethyl]-, 1-ethyl ester;(R)-2-(((R)-1-Ethoxy-1-oxopentan-2-yl)amino)propanoic acid (Perindopril Impurity);2-methylpropan-2-amine (2R,3aS,7aS)-1-(((S)-1-ethoxy-1-oxopentan-2-yl)-L-alanyl)octahydro-1H-indole-2-carboxylate
CBNumber:
CB12709139
Molecular Formula:
C10H19NO4
Molecular Weight:
217.26
MOL File:
145682-38-8.mol
Modify Date:
2023/4/23 13:52:06

(R)-N-(1-Carboxyethyl)-D-norvaline 1-Ethyl Ester Properties

Boiling point 324.1±27.0 °C(Predicted)
Density 1.079±0.06 g/cm3(Predicted)
storage temp. Refrigerator
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
pka 2.15±0.10(Predicted)
color White to Off-White

(R)-N-(1-Carboxyethyl)-D-norvaline 1-Ethyl Ester Chemical Properties,Uses,Production

Uses

(R)-N-(1-Carboxyethyl)-D-norvaline 1-Ethyl Ester is an intermediate in the synthesis of Perindoprilat (P287530), an angiotensin-converting enzyme (ACE) inhibitor. Antihypertensive.

(R)-N-(1-Carboxyethyl)-D-norvaline 1-Ethyl Ester Preparation Products And Raw materials

Raw materials

Preparation Products

(R)-N-(1-Carboxyethyl)-D-norvaline 1-Ethyl Ester Perindopril Impurity 26 Perindopril Impurity 19 Perindopril Related Compound 10 D-Norvaline, N-[(1R)-1-carboxyethyl]-, 1-ethyl ester N-[(R)-1-Carbethoxybutyl]-(R)-alanine 2-methylpropan-2-amine (2R,3aS,7aS)-1-(((S)-1-ethoxy-1-oxopentan-2-yl)-L-alanyl)octahydro-1H-indole-2-carboxylate (R)-2-(((R)-1-Ethoxy-1-oxopentan-2-yl)amino)propanoic acid (Perindopril Impurity) ((R)-1-Ethoxy-1-oxopentan-2-yl)-D-alanine 145682-38-8