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L-Leucyl-L-Leucine methyl ester (hydrochloride)

L-Leucyl-L-Leucine methyl ester (hydrochloride) Structure
CAS No.
6491-83-4
Chemical Name:
L-Leucyl-L-Leucine methyl ester (hydrochloride)
Synonyms
Leu-Leu-ome hydrochloride;H-Leu-leu-OMe hydrochloride;L-Leucyl-L-Leucine methyl ester;L-Leucyl-L-Leucine methyl ester (hydrochloride);L-Leucine, L-leucyl-, methyl ester, monohydrochloride;methyl (2S)-2-[(2S)-2-amino-4-methylpentanamido]-4-methylpentanoate hydrochloride;lymphocytes,leukocytes,monocytes,pathway,LLeucylLLeucine methyl ester hydrochloride,LLOMe,inhibit,polymorphonuclear,stress,Leu-Leu methyl ester,cytotoxic,Inhibitor,L Leucyl L Leucine methyl ester hydrochloride,Endogenous Metabolite,endolysosomal
CBNumber:
CB13152666
Molecular Formula:
C13H27ClN2O3
Molecular Weight:
294.81808
MOL File:
6491-83-4.mol
MSDS File:
SDS
Modify Date:
2023/5/18 11:31:06
Request For Quotation

L-Leucyl-L-Leucine methyl ester (hydrochloride) Properties

Melting point 177-181°C
storage temp. Hygroscopic, Refrigerator, under inert atmosphere
solubility DMSO (Slightly), Water (Slightly)
form Solid
color White to Off-White
Stability Hygroscopic

L-Leucyl-L-Leucine methyl ester (hydrochloride) Chemical Properties,Uses,Production

Description

L-Leucyl-L-Leucine methyl ester (LLME) is a lysosomal condensation product that has been reported to be cytotoxic towards natural killer cells and CD4+ and CD8+ T lymphocytes without affecting helper T cells and B cells. It has also been shown to induce death of monocytes, polymorphonuclear leukocytes, and myeloid tumor cells. Upon entry into cells via receptor-mediated endocytosis, LLME undergoes a condensation process catalyzed by dipeptidyl peptidase I (DPPI) in lysosomes. This condensation leads to lysosomal rupture and DNA fragmentation in DPPI-expressing immune cells such as cytotoxic T cells and natural killer cells.

L-Leucyl-L-Leucine methyl ester (hydrochloride) Preparation Products And Raw materials

Raw materials

Preparation Products

L-Leucyl-L-Leucine methyl ester (hydrochloride) Suppliers

Global( 44)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
BOC Sciences 16314854226; +16314854226 United States 19743 58 Inquiry
Nextpeptide Inc +86-0571-81612335 +8613336028439 China 19915 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 United States 19973 58 Inquiry
Wuhan Topule Biopharmaceutical Co., Ltd +8618327326525 China 8474 58 Inquiry
LEAPCHEM CO., LTD. +86-852-30606658 China 43348 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 57511 58 Inquiry
Shanghai Aladdin Biochemical Technology Co.,Ltd. +86-18521732826 China 48465 58 Inquiry
Olix (Shanghai) Pharmaceutical Technology Co., Ltd 17316404525 China 9810 58 Inquiry
Aribo Pharmatech Co., Ltd. 19951442182 China 2216 58 Inquiry
Supplier Advantage
A.J Chemicals 58
BOC Sciences 58
Nextpeptide Inc 58
TargetMol Chemicals Inc. 58
Wuhan Topule Biopharmaceutical Co., Ltd 58
LEAPCHEM CO., LTD. 58
Aladdin Scientific 58
Shanghai Aladdin Biochemical Technology Co.,Ltd. 58
Olix (Shanghai) Pharmaceutical Technology Co., Ltd 58
Aribo Pharmatech Co., Ltd. 58

6491-83-4(L-Leucyl-L-Leucine methyl ester (hydrochloride))Related Search:

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L-Leucyl-L-Leucine methyl ester (hydrochloride) methyl (2S)-2-[(2S)-2-amino-4-methylpentanamido]-4-methylpentanoate hydrochloride Leu-Leu-ome hydrochloride H-Leu-leu-OMe hydrochloride L-Leucine, L-leucyl-, methyl ester, monohydrochloride L-Leucyl-L-Leucine methyl ester lymphocytes,leukocytes,monocytes,pathway,LLeucylLLeucine methyl ester hydrochloride,LLOMe,inhibit,polymorphonuclear,stress,Leu-Leu methyl ester,cytotoxic,Inhibitor,L Leucyl L Leucine methyl ester hydrochloride,Endogenous Metabolite,endolysosomal 6491-83-4 C13H26N2O3ClH