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(Z)-methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate

CAS No.: 2093243-16-2

Chemical Name:: (Z)-methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate

Synonyms: Nintedanib-013-Z;Nidanibu Impurity 8;Nintedanib impurities11;(Z)-methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate;Nintedanib impurity 12/Methyl (Z)-3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate;1H-Indole-6-carboxylic acid, 2,3-dihydro-3-(hydroxyphenylmethylene)-2-oxo-, methyl ester, (3Z)-

CBNumber:: CB14656048

Molecular Formula:: C17H13NO4

Molecular Weight:: 295.29

MOL File:: 2093243-16-2.mol

Modify Date:: 2023/4/23 13:52:06

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(Z)-methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate Properties

Melting point	>215°C (dec.)
Boiling point	536.9±50.0 °C(Predicted)
Density	1.357±0.06 g/cm3(Predicted)
storage temp.	Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility	DMSO (Slightly), Methanol (Slightly, Heated)
form	Solid
pka	4.50±1.00(Predicted)
color	Yellow to Dark Yellow

(Z)-methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate Chemical Properties,Uses,Production

Uses

(Z)-Methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate is a useful intermediate for the preparation of nintedanib esylate. Nintedanib is a drug for the treatment of idiopathic pulmonary fibrosis.

(Z)-methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

(Z)-methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate Suppliers

Global( 41)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6351	58	Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd	+91-172-5066494	Haryana, India	6773	58	Inquiry
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	China	30253	58	Inquiry
China National Standard Pharmaceutical Corporation Limited	+8615391658522	China	11927	58	Inquiry
Arizest(Shanghai)Pharmatech Co., Ltd	+86-021-60753300	China	220	58	Inquiry
Hubei Weideli Chemical Reagent Co.，Ltd.	027-59222918 13385289472	China	4559	58	Inquiry
Hubei Weideli Chemical Reagent Co.，Ltd.	13339985473	China	4551	58	Inquiry
Tianjin Derchemist Science & Technology Co., Ltd.	22-58627059 13920586291	China	3166	50	Inquiry
Nanjing XiZe Biotechnology CO., Ltd.	025-58362220 15250997978	China	7774	55	Inquiry
Nanjing Huanuo Biomedical Technology Co., Ltd	18913906212	China	6789	58	Inquiry

Supplier	Advantage
CLEARSYNTH LABS LTD.	58
Pharmaffiliates Analytics and Synthetics P. Ltd	58
Career Henan Chemica Co	58
China National Standard Pharmaceutical Corporation Limited	58
Arizest(Shanghai)Pharmatech Co., Ltd	58
Hubei Weideli Chemical Reagent Co.，Ltd.	58
Hubei Weideli Chemical Reagent Co.，Ltd.	58
Tianjin Derchemist Science & Technology Co., Ltd.	50
Nanjing XiZe Biotechnology CO., Ltd.	55
Nanjing Huanuo Biomedical Technology Co., Ltd	58

2093243-16-2((Z)-methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate)Related Search:

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(Z)-methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate Nintedanib impurity 12/Methyl (Z)-3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate Nintedanib-013-Z Nidanibu Impurity 8 Nintedanib impurities11 1H-Indole-6-carboxylic acid, 2,3-dihydro-3-(hydroxyphenylmethylene)-2-oxo-, methyl ester, (3Z)- 2093243-16-2