Sophoridine

Sophoridine Structure
CAS No.
83148-91-8
Chemical Name:
Sophoridine
Synonyms
SOPHORIDINE;I-SOPHORIDINE;SOPHORIDINE(RG);(+)-Sophoridine;MATRIDIN-15-ONE;(-)-SOPHORIDINE;5-EPIDIHYDROSOPHOCARPINE;DIHYDRO-5-EPISOPHOCARPINE;Sophoridine|||Matridin-15-one;Matridin-15-one, (6β,7β,11α)- (9CI)
CBNumber:
CB1495449
Molecular Formula:
C15H24N2O
Molecular Weight:
248.36
MOL File:
83148-91-8.mol
Modify Date:
2023/4/23 13:52:06

Sophoridine Properties

Melting point 108-9°C
Boiling point 396.7±31.0 °C(Predicted)
Density 1.16±0.1 g/cm3(Predicted)
solubility Chloroform (Slightly), Methanol (Slightly), Water (Slightly)
form Solid
pka 9.47±0.20(Predicted)
color Pale Yellow
CAS DataBase Reference 83148-91-8

Sophoridine Chemical Properties,Uses,Production

Description

One of a number of minor alkaloids isolated from Leontice albertii Rgl., this base crystallizes from petroleum ether as colourless prisms. It is dextrorotatory having a specific rotation of [α]D + 59.3° (c 1.3, EtOH) and yields a crystalline methiodide, m.p. 249°C. The structure has been assigned on the basis of chemical analysis and spectroscopic determinations.

Uses

(+)-Sophoridine acts as an anti-inflammatory agent in vitro and in vivo. Anticancer agent, with a promising anti-tumor effect and lower toxicity.

References

Kamalitdinov, Iskandarov, Yunusov, Khim. Prir. Soedin., 3, 352 (1967)
Kamalitdinov, Iskandarov, Yunusov, ibid, 5,409 (1969)

Sophoridine Preparation Products And Raw materials

Raw materials

Preparation Products

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I-SOPHORIDINE DIHYDRO-5-EPISOPHOCARPINE MATRIDIN-15-ONE 5-EPIDIHYDROSOPHOCARPINE (-)-SOPHORIDINE SOPHORIDINE SOPHORIDINE(RG) Matridin-15-one, (6β,7β,11α)- (9CI) (+)-Sophoridine (41R,7aS,13aS,13bS)-Dodecahydro-1H,5H,10H-dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridin-10-one Matridin-15-one, (6b,7b,11a)- (9CI) (41R,7aS,13aS,13bS)-Dodecahydro-1H,5H,10H-dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridin-10-one Sophoridine|||Matridin-15-one 83148-91-8 Inhibitors