WEDELOLACTONE
- CAS No.
- 524-12-9
- Chemical Name:
- WEDELOLACTONE
- Synonyms
- Wedelolactone;Wedelia lactone;Wedelolactone-RM;Wedelolactone CRS;Wedelolactone, ≥98%(HPLC);IKK Inhibitor II, Wedelolactone;5,11,12-Trihydroxy-7-MethoxycouMestan;Wedelolactone, 98%, from Wedelia chinensis (Osbeck.) Merr.;IKK Inhibitor II, Wedelolactone - CAS 524-12-9 - Calbiochem;1,8,9-trihydroxy-3-Methoxy-6H-benzofuro[3,2-c]chroMen-6-one
- CBNumber:
- CB1505300
- Molecular Formula:
- C16H10O7
- Molecular Weight:
- 314.25
- MOL File:
- 524-12-9.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/11/16 15:32:52
WEDELOLACTONE price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | W4016 | Wedelolactone ≥98% (HPLC), powder | 524-12-9 | 1MG | ₹16259.15 | 2022-06-14 | Buy |
| TCI Chemicals (India) | W0015 | Wedelolactone | 524-12-9 | 1MG | ₹4400 | 2022-05-26 | Buy |
| TCI Chemicals (India) | W0015 | Wedelolactone | 524-12-9 | 10MG | ₹10600 | 2022-05-26 | Buy |
WEDELOLACTONE Chemical Properties,Uses,Production
Uses
Wedelolactone is inhibits caspase-11; a key regulator of proinflammatory cytokine IL-1β maturation and apoptosis.
Definition
ChEBI: A member of the class of coumestans that is coumestan with hydroxy substituents as positions 1, 8 and 9 and a methoxy substituent at position 3.
Biochem/physiol Actions
Wedelolactone inhibits NF-κB-mediated gene transcription in cells by blocking the phosphorylation and degradation of IκBα. Irreversible inhibitor of IKKα and β kinase activity (IC50 < 10 μM). Wedelolactone has no effects on p38 MAP kinase or Akt.
WEDELOLACTONE Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 217)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Natural Remedies Pvt Ltd | +91 (80) 4020-9999 | New Delhi, India | 110 | 50 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6257 | 58 | Inquiry |
| Biosyn Research Chemicals | +91 9346022300/+91 9399339999 | Telangana, India | 1340 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6768 | 58 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29884 | 58 | Inquiry |
| Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | CHINA | 1824 | 58 | Inquiry |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | China | 3772 | 58 | Inquiry |
| Xi'an Kono chem co., Ltd., | 029-86107037 13289246953 | China | 2993 | 58 | Inquiry |
| Shaanxi Pioneer Biotech Co., Ltd . | +8613259417953 | China | 3000 | 58 | Inquiry |
| BOC Sciences | +1-631-485-4226 | United States | 19553 | 58 | Inquiry |
524-12-9(WEDELOLACTONE)Related Search:
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1,8,9-Trihydroxy-3-methoxy-6H-benzofuro[3,2-c][1]benzopyran-6-one
6H-Benzofuro(3,2-C)(1)benzopyran-6-one, 1,8,9-trihydroxy-3-methoxy-
5,11,12-Trihydroxy-7-MethoxycouMestan
1,8,9-trihydroxy-3-Methoxy-6H-benzofuro[3,2-c]chroMen-6-one
IKK Inhibitor II, Wedelolactone
Wedelia lactone
Wedelolactone
Wedelolactone, ≥98%(HPLC)
IKK Inhibitor II, Wedelolactone - CAS 524-12-9 - Calbiochem
Wedelolactone, 98%, from Wedelia chinensis (Osbeck.) Merr.
Wedelolactone CRS
1,8,9-trihydroxy-3-methoxy-[1]benzofuro[3,2-c]chromen-6-one
1,8,9-Trihydroxy-3-methoxy-6H-benzofuro[3,2-c]chromen-6-one[Wedelolactone
Wedelolactone-RM
524-12-9
chemical reagent
pharmaceutical intermediate
phytochemical
reference standards from Chinese medicinal herbs (TCM).
standardized herbal extract