Chymotrypsin Substrate II, Fluorogenic

Chymotrypsin Substrate II, Fluorogenic Structure
CAS No.
88467-45-2
Chemical Name:
Chymotrypsin Substrate II, Fluorogenic
Synonyms
SUC-AAPF-AMC;FACTOR XIIA SUBSTRATE;Z-LYS-PHE-ARG-PNA 2HCL;SUC-ALA-ALA-PRO-PHE-MCA;SUC-ALA-ALA-PRO-PHE-AMC;Z-LYS-PHE-ARG-PNA DIHYDROCHLORIDE;Suc-Ala-Ala-Pro-Phe-AMC≥ 99% (HPLC);FACTOR XIIA SUBSTRATE DIHYDROCHLORIDE;CHYMOTRYPSIN SUBSTRATE II, FLUOROGENIC;5:PN:WO0197794 SEQID:34 claimed protein
CBNumber:
CB1701335
Molecular Formula:
C34H39N5O9
Molecular Weight:
661.7
MOL File:
88467-45-2.mol
Modify Date:
2024/7/2 8:55:01

Chymotrypsin Substrate II, Fluorogenic Properties

Boiling point 1093.0±65.0 °C(Predicted)
Density 1.347±0.06 g/cm3(Predicted)
storage temp. -20°C
solubility Clear, colorless solution (10 mg/mL in Methanol)
form White lyophilized solid
pka 4.69±0.10(Predicted)
color White to off-white

SAFETY

Risk and Safety Statements

WGK Germany  3

Chymotrypsin Substrate II, Fluorogenic price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) S9761 N-Succinyl-Ala-Ala-Pro-Phe-7-amido-4-methylcoumarin Leucine aminopeptidase substrate 88467-45-2 1MG ₹5564.05 2022-06-14 Buy
Sigma-Aldrich(India) S9761 N-Succinyl-Ala-Ala-Pro-Phe-7-amido-4-methylcoumarin Leucine aminopeptidase substrate 88467-45-2 5MG ₹19777.28 2022-06-14 Buy
Sigma-Aldrich(India) 230914 Chymotrypsin Substrate II, Fluorogenic - CAS 88467-45-2 - Calbiochem Sensitive fluorogenic substrate for the quantitative determination of chymotrypsin activity. 88467-45-2 25MG ₹11730 2022-06-14 Buy
Product number Packaging Price Buy
S9761 1MG ₹5564.05 Buy
S9761 5MG ₹19777.28 Buy
230914 25MG ₹11730 Buy

Chymotrypsin Substrate II, Fluorogenic Chemical Properties,Uses,Production

Description

Chymotrypsin Substrate II, Fluorogenic finds widespread utility across diverse scientific research applications, encompassing the exploration of protein-protein interactions, enzyme kinetics, and receptor binding. Notably, its cost-effectiveness and user-friendly nature render it an appealing choice for researchers. Additionally, this peptide has been instrumental in delving into the intricate world of cell signaling pathways and unraveling the mechanisms governing gene expression regulation. It is postulated to function as a substrate for enzymes while also engaging with receptors. The prevailing belief suggests that the peptide effectively binds to specific receptors, subsequently triggering their activation and instigating consequential alterations in cellular signaling pathways.

Chemical Properties

White powder

Uses

Chymotrypsin Substrate II, Fluorogenic (cas# 88467-45-2) is a useful compound in organic synthesis and acts as a substrate for chymotrypsin enzyme.

Biological Activity

Sensitive fluorogenic substrate for the quantitative determination of chymotrypsin activity (excitation maximum: ~380 nm; emission maximum: ~460 nm).

References

[1] G B IRVINE C H W M Ennis. Visual detection of peptidase activity using fluorogenic substrates in a microtiter plate assay.[J]. Analytical biochemistry, 1990, 185 2: 304-307. DOI:10.1016/0003-2697(90)90298-n.
[2] LASZLO GRAF. Selective alteration of substrate specificity by replacement of aspartic acid-189 with lysine in the binding pocket of trypsin[J]. Biochemistry Biochemistry, 1987, 26 9: 2616-2623. DOI:10.1021/bi00383a031.
[3] OSHIMA G. Interaction of alpha-chymotrypsin with dimyristoyl phosphatidylcholine vesicles.[J]. Journal of biochemistry, 1984, 95 4: 1131-1136. DOI:10.1093/oxfordjournals.jbchem.a134701.
[4] OSHIMA G. Stimulation by phospholipid vesicles of proteolysis of egg white lysozyme by chymotrypsin.[J]. Journal of biochemistry, 1983, 5 1: 1615-1620. DOI:10.1093/OXFORDJOURNALS.JBCHEM.A134509.

Chymotrypsin Substrate II, Fluorogenic Preparation Products And Raw materials

Raw materials

Preparation Products

Chymotrypsin Substrate II, Fluorogenic Suppliers

Global( 56)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Career Henan Chemica Co +86-0371-86658258 +8613203830695 China 30250 58 Inquiry
BOC Sciences 16314854226; +16314854226 United States 19743 58 Inquiry
Chengdu Youngshe Chemical Co., Ltd. +8618108235634 China 2345 58 Inquiry
Nanjing TGpeptide +86-13347807150 +86-13347807150 China 3279 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 57511 58 Inquiry
Hangzhou Beiputai Biopharmaceutical Co., Ltd 0571-85350119 13305819357 China 3850 58 Inquiry
Shanghai Aladdin Biochemical Technology Co.,Ltd. +86-18521732826 China 48465 58 Inquiry
Shanghai Yaji Biological Technology Co., Ltd. 021-34661275 15301693058 China 9476 58 Inquiry
Chengdu Peter-like Biotechnology Co., Ltd. 028-81700200 18108052721 China 5178 58 Inquiry
SUCCINYL-L-ALANYL-L-ALANYL-L-PROLYL-L-PHENYLALANINE 4-METHYLCOUMARYL-7-AMIDE SUC-AAPF-AMC SUC-ALA-ALA-PRO-PHE-MCA SUC-ALA-ALA-PRO-PHE-7-AMINO-4-METHYLCOUMARIN SUC-ALA-ALA-PRO-PHE-AMC N-SUCCINYL-ALA-ALA-PRO-PHE 7-AMIDO-4-METHYLCOUMARIN Z-LYS-PHE-ARG-PNA 2HCL CHYMOTRYPSIN SUBSTRATE II, FLUOROGENIC FACTOR XIIA SUBSTRATE DIHYDROCHLORIDE N-SUCCINYL-ALA-ALA-PRO-PHE 7-AMIDO-4-*ME THYLCOUMARI FACTOR XIIA SUBSTRATE succinylalanylalanyl-prolyl-phenylalanine-4-methylcoumaryl-7-amide Z-LYS-PHE-ARG-PNA DIHYDROCHLORIDE Suc-Ala-Ala-Pro-Phe-AMC≥ 99% (HPLC) Chymotrypsin Substrate II, Fluorogenic - CAS 88467-45-2 - Calbiochem L-Phenylalaninamide, N-(3-carboxy-1-oxopropyl)-L-alanyl-L-alanyl-L-prolyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)- 5:PN:WO0197794 SEQID:34 claimed protein 4-[[(2S)-1-[[(2S)-1-[(2S)-2-[[(2S)-2-[(4-methyl-2-oxochromen-7-yl)amino]-3-phenylpropanoyl]carbamoyl]pyrrolidin-1-yl]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-4-oxobutanoic acid N-(3-Carboxy-1-oxopropyl)-L-alanyl-L-alanyl-L-prolyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-Phenylalaninamide 88467-45-2 C34H39N5O9 Enzymes, Inhibitors, and Substrates Enzyme Substrates Leucine Aminopeptidase Substrates by Enzyme BioChemical Biochemicals and Reagents Chymotrypsin, alphaEnzyme Substrates Leucine aminopeptidase Leucine AminopeptidaseEnzyme Substrates Enzyme Substrates Protease Substrates Substrates by Enzyme