2,2-DIFLUOROACETOPHENONE

2,2-DIFLUOROACETOPHENONE Structure
CAS No.
395-01-7
Chemical Name:
2,2-DIFLUOROACETOPHENONE
Synonyms
2,2-DIFLUOROACETOPHENONE;A,A-DIFLUOROACETOPHENONE;2,2-Difluoroacetophenone97%;2,2-Difluoroacetophenone,95%;2,2-Difluoroacetophenone 97%;2,2-DIFLUORO-1-PHENYLETHANONE;Ethanone, 2,2-difluoro-1-phenyl-;2,2-Difluoro-1-phenylethan-1-one;ALPHA,ALPHA-DIFLUOROACETOPHENONE;Ethanone, 2,2-difluoro-1-phenyl- (9CI)
CBNumber:
CB1750292
Molecular Formula:
C8H6F2O
Molecular Weight:
156.13
MOL File:
395-01-7.mol
MSDS File:
SDS
Modify Date:
2023/4/23 13:52:06

2,2-DIFLUOROACETOPHENONE Properties

Melting point 48-50°C
Boiling point 53-54°C/12mm
Density 1.180±0.06 g/mL
refractive index 1.4955
Flash point 53-54°C/12mm
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
form liquid
Water Solubility Immiscible with water.
CAS DataBase Reference 395-01-7

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
HazardClass  IRRITANT
HS Code  2914790090
NFPA 704
1
2 0

2,2-DIFLUOROACETOPHENONE price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 793841 2,2-Difluoroacetophenone 395-01-7 1G ₹8454.33 2022-06-14 Buy
Sigma-Aldrich(India) 793841 2,2-Difluoroacetophenone 395-01-7 5G ₹25395.45 2022-06-14 Buy
Product number Packaging Price Buy
793841 1G ₹8454.33 Buy
793841 5G ₹25395.45 Buy

2,2-DIFLUOROACETOPHENONE Chemical Properties,Uses,Production

Uses

2,2-Difluoroacetophenone acts as an intermediate in the preparation of various substances such as pharmaceuticals. Further, it is used in the one-pot synthesis of difluoromethylated arenes from aryl chlorides and bromides. In addition to this, it undergoes reduction with (-)-diisopinocampheylchloroborane chloride to get R-alcohols of purity 85% ee.

Synthesis Reference(s)

Tetrahedron, 52, p. 15, 1996 DOI: 10.1016/0040-4020(95)00884-B

2,2-DIFLUOROACETOPHENONE Preparation Products And Raw materials

Raw materials

Preparation Products

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A,A-DIFLUOROACETOPHENONE ALPHA,ALPHA-DIFLUOROACETOPHENONE Ethanone, 2,2-difluoro-1-phenyl- (9CI) 2,2-Difluoroacetophenone,95% 2,2-Difluoro-1-phenylethan-1-one 2,2-Difluoroacetophenone 97% 2,2-Difluoro-1-phenylethan-1-one, 2,2-Difluoro-1-phenyl-1-oxoethane 2,2-DIFLUOROACETOPHENONE 2,2-DIFLUORO-1-PHENYLETHANONE 2,2-Difluoroacetophenone97% Ethanone, 2,2-difluoro-1-phenyl- 395-01-7 ACETYLHALIDE