COCAINE HYDROCHLORIDE
- CAS No.
- 53-21-4
- Chemical Name:
- COCAINE HYDROCHLORIDE
- Synonyms
- Cocaine HCl;8-Azabicyclo[3.2.1]octane-2-carboxylicacid, 3-(benzoyloxy)-8-Methyl-, Methyl ester, hydrochloride (1:1),(1R,2R,3S,5S)-;MCV 4526;NIH 8211;NSC 25263;(ester)hcl;saldemerck;Sal de Merc;cocainemuriate;cocainechloride
- CBNumber:
- CB1781450
- Molecular Formula:
- C17H22ClNO4
- Molecular Weight:
- 339.81
- MOL File:
- 53-21-4.mol
- Modify Date:
- 2023/6/8 9:02:51
| Melting point | 200-2020C |
|---|---|
| alpha | D -72° (c = 2 in aq soln pH 4.5) |
| storage temp. | 2-8°C |
| solubility | Very soluble in water, freely soluble in alcohol, slightly soluble in methylene chloride. |
| form | Powder |
| Water Solubility | Soluble to 100 mM in water |
| CAS DataBase Reference | 53-21-4 |
| EPA Substance Registry System | 8-Azabicyclo[3.2.1]octane-2-carboxylic acid, 3-(benzoyloxy)-8-methyl-, methyl ester, hydrochloride (1:1), (1R,2R,3S,5S)- (53-21-4) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS08,GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301-H360-H317 | |||||||||
| Precautionary statements | P264-P270-P301+P310-P321-P330-P405-P501-P261-P272-P280-P302+P352-P333+P313-P321-P363-P501 | |||||||||
| Hazard Codes | T,F | |||||||||
| Risk Statements | 60-25-43-39/23/24/25-23/24/25-11 | |||||||||
| Safety Statements | 7-16-36/37-45-22-53 | |||||||||
| RIDADR | UN 1544 6.1/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | YM3050000 | |||||||||
| HazardClass | 6.1(a) | |||||||||
| PackingGroup | II | |||||||||
| HS Code | 2939710000 | |||||||||
| NFPA 704 |
|
COCAINE HYDROCHLORIDE Chemical Properties,Uses,Production
Description
Cocaine (hydrochloride) (Item No. 22165) is an analytical reference standard categorized as a tropane. Cocaine has a high potential for abuse and has been found in samples seized by law enforcement. Cocaine is regulated as a Schedule II compound in the United States. This product is intended for research and forensic applications.
Chemical Properties
White Solid
Uses
Inhibits the dopamine, norepinephrine, and serotonin transporters. Unlike amphetamines, it has no effect on catecholamine release. Controlled substance. Anesthetic (local)
Definition
ChEBI: The hydrochloride salt of cocaine. It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat. It also has powerful central nervous system effects similar to the amphetamines and is drug of abuse.
Biological Activity
Competitive inhibitor of monoamine neurotransmitter transporters. Inhibits dopamine (DAT), serotonin (SERT) and noradrenalin (NET) transporters with K i values are 267, 392 and 872 nM respectively. Psychostimulant.
COCAINE HYDROCHLORIDE Preparation Products And Raw materials
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