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4'-hydroxyflurbiprofen

4'-hydroxyflurbiprofen Structure
CAS No.
52807-12-2
Chemical Name:
4'-hydroxyflurbiprofen
Synonyms
FPH;Flurbiprofen 4-Hydroxy;4'-Hydroxy flurbiprofen;Flurbiprofen EP Impurity G;4-Hydroxyflurbiprofen 13CD3;13C,2H3]-4'-Hydroxyflurbiprofen;4’-Hydroxy Flurbiprofen (10mM in DMSO);2-(4'-Hydroxy-2-fluoro-4-biphenylyl)propionic Acid;2-Fluoro-4'-hydroxy-α-Methyl-[1,1'-biphenyl]-4-acetic Acid;2-(2-fluoro-4'-hydroxy-[1,1'-biphenyl]-4-yl)propanoic acid
CBNumber:
CB21325234
Molecular Formula:
C15H13FO3
Molecular Weight:
260.26
MOL File:
52807-12-2.mol
MSDS File:
SDS
Modify Date:
2023/6/8 9:03:09

4'-hydroxyflurbiprofen Properties

Melting point 177-178°C
Boiling point 417.6±40.0 °C(Predicted)
Density 1.288±0.06 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility DMF: 25 mg/ml; DMSO: 10 mg/ml; Ethanol: 25 mg/ml; PBS (pH 7.2): 0.5 mg/ml
form A crystalline solid
pka 4.20±0.10(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS06
Signal word  Danger
Hazard statements  H301
Precautionary statements  P264-P270-P301+P310-P321-P330-P405-P501
NFPA 704
0
2 0

4'-hydroxyflurbiprofen Chemical Properties,Uses,Production

Chemical Properties

White to Off-White Solid

Uses

4'-hydroxyflurbiprofen is a metabolite of Flurbiprofen (F598700), an anti-inflammatory used as an analgesic.

4'-hydroxyflurbiprofen Preparation Products And Raw materials

Raw materials

Preparation Products

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(1,1'-Biphenyl)-4-acetic acid, 2-fluoro-4'-hydroxy-alpha-methyl- 2-(4'-Hydroxy-2-fluoro-4-biphenylyl)propionic Acid 2-Fluoro-4'-hydroxy-α-Methyl-[1,1'-biphenyl]-4-acetic Acid FPH Flurbiprofen EP Impurity G 2-(2-fluoro-4'-hydroxy-[1,1'-biphenyl]-4-yl)propanoic acid Flurbiprofen 4-Hydroxy [1,1'-Biphenyl]-4-acetic acid, 2-fluoro-4'-hydroxy-α-methyl- 4’-Hydroxy Flurbiprofen (10mM in DMSO) 4-Hydroxyflurbiprofen 13CD3 13C,2H3]-4'-Hydroxyflurbiprofen 4'-Hydroxy flurbiprofen 52807-12-2 Aromatics Intermediates & Fine Chemicals Metabolites & Impurities Pharmaceuticals