ChemicalBook > Product Catalog >Pharmaceutical intermediates >Heterocyclic compound >Pyrimidines >Iodine pyrimidine >5-Chloro-2-iodopyrimidine

5-Chloro-2-iodopyrimidine

5-Chloro-2-iodopyrimidine Structure
CAS No.
874676-81-0
Chemical Name:
5-Chloro-2-iodopyrimidine
Synonyms
5-Chloro-2-iodopyrimidine;Pyrimidine, 5-chloro-2-iodo-;5-Chloro-2-iodopyrimidine 97%;5-Chloro-2-iodopyrimidine ISO 9001:2015 REACH
CBNumber:
CB21483439
Molecular Formula:
C4H2ClIN2
Molecular Weight:
240.43
MOL File:
874676-81-0.mol
MSDS File:
SDS
Modify Date:
2024/4/8 17:36:13

5-Chloro-2-iodopyrimidine Properties

Boiling point 316.6±34.0 °C(Predicted)
Density 2.187±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
pka -2.56±0.22(Predicted)
form Powder
color White
Water Solubility Slightly soluble in water.
Sensitive Light Sensitive
InChI InChI=1S/C4H2ClIN2/c5-3-1-7-4(6)8-2-3/h1-2H
InChIKey BWDLBDLGVMLSCS-UHFFFAOYSA-N
SMILES C1(I)=NC=C(Cl)C=N1

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335-H302
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes  Xn
Risk Statements  22
HS Code  2933599590
NFPA 704
1
2 0

5-Chloro-2-iodopyrimidine price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) SYX00017 5-Chloro-2-iodopyrimidine AldrichCPR 874676-81-0 1G ₹15003.45 2022-06-14 Buy
ALFA India ALF-H64185-MD 5-Chloro-2-iodopyrimidine, 98% 874676-81-0 250mg ₹1638 2022-05-26 Buy
ALFA India ALF-H64185-06 5-Chloro-2-iodopyrimidine, 98% 874676-81-0 5g ₹14504 2022-05-26 Buy
ALFA India ALF-H64185-03 5-Chloro-2-iodopyrimidine, 98% 874676-81-0 1g ₹3112 2022-05-26 Buy
Product number Packaging Price Buy
SYX00017 1G ₹15003.45 Buy
ALF-H64185-MD 250mg ₹1638 Buy
ALF-H64185-06 5g ₹14504 Buy
ALF-H64185-03 1g ₹3112 Buy

5-Chloro-2-iodopyrimidine Chemical Properties,Uses,Production

Description

5-Chloro-2-iodopyrimidine is an organic molecule that belongs to the class of trifluoromethylated molecules. It is a halogenated derivative of pyrimidine and has a molecular formula of C4H2ClIN2. 5-Chloro-2-iodopyrimidine can be catalyzed with copper, which is responsible for its unique reactivity. The synthesis of this molecule has been shown to be efficient in organic chemistry.

Uses

Useful Intermediate for organic synthesis and pharmaceutical.

Preparation

A flask was charged with 57% HI (48 ml) and then cooled to 0°C in an ice-salt mixture. Dichloropyrimidine (6 g) was added to the mixture. After 4h, the obtained yellow suspension was treated carefully with K2CO3 solution (32 g, 60 ml), and the pale yellow solid was collected by filtration. The solid was washed with water and dried to give compound 5-Chloro-2-iodopyrimidine.
5-Chloro-2-iodopyrimidine

Application

As a chemical intermediate used in the pharmaceutical and agrochemical industriesIt, 5-Chloro-2-iodopyrimidine is commonly used as a building block in the synthesis of biologically active molecules, such as kinase inhibitors, antiviral agents, and herbicides.

Origin

5-Chloro-2-iodopyrimidine was discovered by  chemists in 2006 and has been used as a reagent for the efficient trifluoromethylation of organic molecules.

5-Chloro-2-iodopyrimidine Preparation Products And Raw materials

Global( 124)Suppliers
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JSK Chemicals +919879767970 Gujarat, India 3756 58 Inquiry
Suven Pharmaceuticals Limited +91-91-40-23541142 +91-4023541142 Telangana, India 218 58 Inquiry
Alfa Aesar 1 800 209 7001 Maharashtra, India 6913 58 Inquiry
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Fuxin Pharmaceutical +86-021-021-50872116 +8613122107989 China 10297 58 Inquiry
5-Chloro-2-iodopyrimidine 5-Chloro-2-iodopyrimidine 97% Pyrimidine, 5-chloro-2-iodo- 5-Chloro-2-iodopyrimidine ISO 9001:2015 REACH 874676-81-0 C4H2ClIN C4H2ClIN2 Heterocycle-Pyrimidine series Pyridines, Pyrimidines, Purines and Pteredines Heterocyclic Compounds Pyrimidine