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Ethyl (3-fluorobenzoyl)acetate

Ethyl (3-fluorobenzoyl)acetate Structure
CAS No.
33166-77-7
Chemical Name:
Ethyl (3-fluorobenzoyl)acetate
Synonyms
Ethyl m-fluorobenzoyl acetate;Ethyl 2-3-fluorobenzoylacetate;ETHYL (3-FLUOROBENZOYL)ACETATE;Ethyl 3-fluoro-β-oxobenzenepropanoate;(m-Fluorobenzoyl)acetic acid ethyl ester;ETHYL 3-(3-FLUOROPHENYL)-3-OXOPROPANOATE;3-(3-Fluorophenyl)-3-oxopropanoic acid ethyl ester;Benzenepropanoic acid, 3-fluoro-β-oxo-, ethyl ester;Benzenepropanoic acid, 3-fluoro-β-oxo-, ethyl ester;3-(3-Fluoro-phenyl)-3-oxo-propionic acid ethyl bster
CBNumber:
CB2148920
Molecular Formula:
C11H11FO3
Molecular Weight:
210.2
MOL File:
33166-77-7.mol
Modify Date:
2023/10/25 15:33:13

Ethyl (3-fluorobenzoyl)acetate Properties

Boiling point 262-263 °C(lit.)
Density 1.166 g/mL at 25 °C(lit.)
refractive index n20/D 1.5172(lit.)
Flash point >230 °F
storage temp. Sealed in dry,Room Temperature
form Liquid
pka 10.10±0.46(Predicted)
color Colorless to orange
CAS DataBase Reference 33166-77-7(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P
WGK Germany  3
TSCA  Yes
HS Code  2916399090
NFPA 704
1
0 0

Ethyl (3-fluorobenzoyl)acetate price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 559237 Ethyl (3-fluorobenzoyl)acetate 33166-77-7 1G ₹10879.13 2022-06-14 Buy
Sigma-Aldrich(India) 559237 Ethyl (3-fluorobenzoyl)acetate 33166-77-7 5G ₹11864.2 2022-06-14 Buy
Product number Packaging Price Buy
559237 1G ₹10879.13 Buy
559237 5G ₹11864.2 Buy

Ethyl (3-fluorobenzoyl)acetate Chemical Properties,Uses,Production

Uses

Reactant for:

  • Preparation of biologically active molecules

Synthesis

To a stirring suspension of NaH and CO(OEt)2 in toluene was added dropwise a solution of substituted acetophenone in toluene under reflux. The mixture was allowed to reflux and was stirred for 20 min after the addition was complete. When cooled to room temperature, the mixture was acidified with glacial HOAc. After ice-cold water was added, the mixture was extracted with toluene. The extract was then dried over anhydrous MgS04. After the toluene was evaporated in vacuo to give the corresponding substituted Ethyl (3-fluorobenzoyl)acetate.

Ethyl (3-fluorobenzoyl)acetate Preparation Products And Raw materials

Raw materials

Preparation Products

Ethyl (3-fluorobenzoyl)acetate Suppliers

Global( 148)Suppliers
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CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
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3-(3-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER ETHYL 3-(3-FLUOROPHENYL)-3-OXOPROPANOATE ETHYL (3-FLUOROBENZOYL)ACETATE (m-Fluorobenzoyl)acetic acid ethyl ester 3-(3-Fluorophenyl)-3-oxopropanoic acid ethyl ester Ethyl 2-3-fluorobenzoylacetate Ethyl 3-fluoro-β-oxobenzenepropanoate Ethyl m-fluorobenzoyl acetate Benzenepropanoic acid, 3-fluoro-β-oxo-, ethyl ester 3-(3-Fluoro-phenyl)-3-oxo-propionic acid ethyl bster Benzenepropanoic acid, 3-fluoro-β-oxo-, ethyl ester 33166-77-7 FC6H4COCH2CO2C2H5 Esters Organic Building Blocks C10 to C11 Carbonyl Compounds Building Blocks C10 to C11 Carbonyl Compounds Esters