CAY10566

CAS No.: 944808-88-2

Chemical Name:: CAY10566

Synonyms: CAY10566;Inhibitor,inhibit,Stearoyl-CoA Desaturase (SCD),CAY10566,CAY 10566,CAY-10566;2-(6-(4-(2-CHLORO-5-FLUOROPHENOXY)PIPERIDIN-1-YL)PYRIDAZIN-3-YL)-5-METHYL-1,3,4-OXADIAZOLE;3-[4-(2-CHLORO-5-FLUOROPHENOXY)-1-PIPERIDINYL]-6-(5-METHYL-1,3,4-OXADIAZOL-2-YL)-PYRIDAZINE;Pyridazine, 3-[4-(2-chloro-5-fluorophenoxy)-1-piperidinyl]-6-(5-methyl-1,3,4-oxadiazol-2-yl)-

CBNumber:: CB22468453

Molecular Formula:: C18H17ClFN5O2

Molecular Weight:: 389.81

MOL File:: 944808-88-2.mol

MSDS File:: SDS

Modify Date:: 2023/5/18 11:31:07

Request For Quotation

CAY10566 Properties

Melting point	160 - 170°C
Boiling point	600.2±65.0 °C(Predicted)
Density	1.369±0.06 g/cm3(Predicted)
storage temp.	2-8°C
solubility	DMSO (Slightly), Methanol (Slightly)
pka	2.01±0.10(Predicted)
form	Solid
color	Pale Beige

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P305+P351+P338

CAY10566 price More Price(2)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	SML3223	CAY10566 ≥98% (HPLC)	944808-88-2	5MG	₹18922.1	2022-06-14	Buy
Sigma-Aldrich(India)	SML3223	CAY10566 ≥98% (HPLC)	944808-88-2	25MG	₹76013.15	2022-06-14	Buy

Product number	Packaging	Price	Buy
SML3223	5MG	₹18922.1	Buy
SML3223	25MG	₹76013.15	Buy

CAY10566 Chemical Properties,Uses,Production

Description

Stearoyl-CoA desaturase (SCD) catalyzes the committed step of the conversion of saturated, long-chain fatty acids to monounsaturated fatty acids. The SCD1 gene is thought to play a key role in lipid homeostasis and body weight regulation. Thus, modulating SCD1 activity pharmacologically may be a useful tool for regulating type 2 diabetes, dyslipidemia, and obesity. CAY10566 is a potent and selective inhibitor of SCD1 that demonstrates IC₅₀ values of 4.5 and 26 nM in mouse and human enzymatic assays, respectively. This compound inhibits the conversion of saturated, long-chain fatty acyl-CoAs to monounsaturated, long-chain fatty acyl-CoAs in HepG2 cells with IC₅₀ values of 7.9 and 6.8 nM, respectively, when heptadecanoic acid and palmitic acid are used as the substrate.

Uses

CAY10566, is a stearoyl-CoA desaturase (SCD) inhibitor.

CAY10566 Preparation Products And Raw materials

Raw materials

1-(6-Chloro-3-pyridazinyl)-4-piperidinol 2-Chloro-5-fluorophenol

Preparation Products

CAY10566 Suppliers

Global( 50)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	China	32835	60	Inquiry
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	United States	19892	58	Inquiry
InvivoChem	+1-708-310-1919 +1-13798911105	United States	6393	58	Inquiry
LEAPCHEM CO., LTD.	+86-852-30606658	China	43348	58	Inquiry
Jilin Chinese Academy of Sciences-yanshen Technology	+undefined18143011203	China	42057	58	Inquiry
Aladdin Scientific	+1-+1(833)-552-7181	United States	52927	58	Inquiry
RD International Technology Co., Limited	18024082417	China	9268	58	Inquiry
Shanghai Chaolan Chemical Technology Center	QQ:65489617 15618227136	China	9949	58	Inquiry
Jiangsu Aikon Biopharmaceutical R&D Co.,Ltd.	025-66061636 18013972705	China	10238	58	Inquiry
Bide Pharmatech Ltd.	400-1647117 13681763483	China	62163	58	Inquiry

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
TargetMol Chemicals Inc.	58
InvivoChem	58
LEAPCHEM CO., LTD.	58
Jilin Chinese Academy of Sciences-yanshen Technology	58
Aladdin Scientific	58
RD International Technology Co., Limited	58
Shanghai Chaolan Chemical Technology Center	58
Jiangsu Aikon Biopharmaceutical R&D Co.,Ltd.	58
Bide Pharmatech Ltd.	58

2-(6-(4-(2-CHLORO-5-FLUOROPHENOXY)PIPERIDIN-1-YL)PYRIDAZIN-3-YL)-5-METHYL-1,3,4-OXADIAZOLE 3-[4-(2-CHLORO-5-FLUOROPHENOXY)-1-PIPERIDINYL]-6-(5-METHYL-1,3,4-OXADIAZOL-2-YL)-PYRIDAZINE CAY10566 Pyridazine, 3-[4-(2-chloro-5-fluorophenoxy)-1-piperidinyl]-6-(5-methyl-1,3,4-oxadiazol-2-yl)- Inhibitor,inhibit,Stearoyl-CoA Desaturase (SCD),CAY10566,CAY 10566,CAY-10566 944808-88-2 C18H17ClFN5O2