(3alpha,5beta,7alpha,12alpha)-3,7,12-Tris(formyloxy)cholan-24-oic acid

(3alpha,5beta,7alpha,12alpha)-3,7,12-Tris(formyloxy)cholan-24-oic acid Structure
CAS No.
2097-89-4
Chemical Name:
(3alpha,5beta,7alpha,12alpha)-3,7,12-Tris(formyloxy)cholan-24-oic acid
Synonyms
Tri-O-formylcholic Acid;OHJFKWAMNYLNEV-OCCHXLOTSA-N;3a,7a,12a-tri(forMyloxy)-5b-cholanic acid;3α,7α,12α-tri(formyloxy)-5β-cholan-24-oic acid;(3α,5β,7α,12α)-3,7,12-Tris(forMyloxy)cholan-24-oic acid;Cholan-24-oic acid, 3,7,12-tris(formyloxy)-, (3α,5β,7α,12α)-;(3alpha,5beta,7alpha,12alpha)-3,7,12-Tris(formyloxy)cholan-24-oic acid;(4R)-4-((3R,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-tris(formyloxy)-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid
CBNumber:
CB22510037
Molecular Formula:
C27H40O8
Molecular Weight:
492.6
MOL File:
2097-89-4.mol
MSDS File:
SDS

(3alpha,5beta,7alpha,12alpha)-3,7,12-Tris(formyloxy)cholan-24-oic acid Properties

Melting point 201-203 °C
Boiling point 593.7±50.0 °C(Predicted)
Density 1.21
storage temp. 2-8°C
pka 4.76±0.10(Predicted)

(3alpha,5beta,7alpha,12alpha)-3,7,12-Tris(formyloxy)cholan-24-oic acid Chemical Properties,Uses,Production

Uses

Tri-O-formylcholic Acid is an intermediate used in the synthesis of 3α,7α,12α-Trihydroxycoprostanic Acid-d3 (T795157), which is a labelled analogue of 3α,7α,12α-Trihydroxycoprostanic Acid (T795155), a precursor of Cholic Acid (C432600), it undergoes side chain oxidation during the synthesis of bile acids. It was found that Zellweger’s syndrome patients have abnormal mitochondrial structure, the organelle that is responsible for the side chain oxidation, and as a consequence, excess amounts of 3α,7α,12α-Trihydroxycoprostanic Acid.

(3alpha,5beta,7alpha,12alpha)-3,7,12-Tris(formyloxy)cholan-24-oic acid Preparation Products And Raw materials

Raw materials

Preparation Products

(3alpha,5beta,7alpha,12alpha)-3,7,12-Tris(formyloxy)cholan-24-oic acid Suppliers

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(3alpha,5beta,7alpha,12alpha)-3,7,12-Tris(formyloxy)cholan-24-oic acid 3a,7a,12a-tri(forMyloxy)-5b-cholanic acid (3α,5β,7α,12α)-3,7,12-Tris(forMyloxy)cholan-24-oic acid Tri-O-formylcholic Acid Cholan-24-oic acid, 3,7,12-tris(formyloxy)-, (3α,5β,7α,12α)- OHJFKWAMNYLNEV-OCCHXLOTSA-N 3α,7α,12α-tri(formyloxy)-5β-cholan-24-oic acid (4R)-4-((3R,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-tris(formyloxy)-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid 2097-89-4