ChemicalBook > Product Catalog >Analytical Chemistry >Standard >Pharmaceutical Impurity Reference Standards >3-(3-Chloropropyl)-7,8-dimethoxy-2,3,4,5-tetrahydro-1H-3-benzazepin-2-one

3-(3-Chloropropyl)-7,8-dimethoxy-2,3,4,5-tetrahydro-1H-3-benzazepin-2-one

3-(3-Chloropropyl)-7,8-dimethoxy-2,3,4,5-tetrahydro-1H-3-benzazepin-2-one Structure
CAS No.
85175-65-1
Chemical Name:
3-(3-Chloropropyl)-7,8-dimethoxy-2,3,4,5-tetrahydro-1H-3-benzazepin-2-one
Synonyms
Ivabradin-5;Ivabradine Impurity m;Ivabradine Impurity 61;Ivabradine related compound 8;(Z)-7,8-dimethoxy-1H-benzo[d]azepin-2(3H)-one;3-(3-chloropropyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2h-3-ben...;3-(3-Chloropropyl)-7,8-diMethoxy-4,5-dihydro-1H-benzo[d]azepin-2(3H)-one;3-(3-Chloropropyl)-7,8-dimethoxy-2,3,4,5-tetrahydro-1H-3-benzazepin-2-one;3-(3-Chloropropyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-one;7,8-dimethoxy-3-(3-chloropropyl)-1,3,4,5-tetrahydro-2H-3-benzazepin-2-one
CBNumber:
CB22554350
Molecular Formula:
C15H20ClNO3
Molecular Weight:
297.78
MOL File:
85175-65-1.mol
MSDS File:
SDS
Modify Date:
2023/5/4 15:12:36

3-(3-Chloropropyl)-7,8-dimethoxy-2,3,4,5-tetrahydro-1H-3-benzazepin-2-one Properties

Melting point 100-102℃
Density 1.167
storage temp. 2-8°C

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H319-H315-H335-H302
Precautionary statements  P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362-P264-P270-P301+P312-P330-P501

3-(3-Chloropropyl)-7,8-dimethoxy-2,3,4,5-tetrahydro-1H-3-benzazepin-2-one Chemical Properties,Uses,Production

Uses

3-(3-Chloropropyl)-1,3,4,5-tetrahydro-7,8-dimethoxy-2H-3-benzazepin-2-one is an impurity in the synthesis of Ivabradine (I940500), a selective bradycardic agent with direct effect on the pacemaker If current of the sinoatrial node. Antianginal.

3-(3-Chloropropyl)-7,8-dimethoxy-2,3,4,5-tetrahydro-1H-3-benzazepin-2-one Preparation Products And Raw materials

Raw materials

Preparation Products

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3-(3-Chloropropyl)-7,8-diMethoxy-4,5-dihydro-1H-benzo[d]azepin-2(3H)-one 3-(3-chloropropyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one Ivabradine Impurity m 3-(3-Chloropropyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-one 3-(3-Chloropropyl)-7,8-dimethoxy-2,3,4,5-tetrahydro-1H-3-benzazepin-2-one 2H-3-Benzazepin-2-one, 3-(3-chloropropyl)-1,3,4,5-tetrahydro-7,8-dimethoxy- (Z)-7,8-dimethoxy-1H-benzo[d]azepin-2(3H)-one Ivabradine related compound 8 3-(3-((((S)-3,4-dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)(methyl)amino)propyl)-1-hydroxy-7,8-dimethoxy-4,5-dihydro-1H-benzo[d]azepin-2(3H)-one Ivabradin-5 Ivabradine Impurity 61 3-(3-chloropropyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2h-3-ben... Ivabradine Impurity 1 3-(3-chloropropyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2H- benzo[d]azepin-2-one 7,8-dimethoxy-3-(3-chloropropyl)-1,3,4,5-tetrahydro-2H-3-benzazepin-2-one 85175-65-1