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9,11-Dehydro-17α-cyanoMethyl Estradiol

9,11-Dehydro-17α-cyanoMethyl Estradiol Structure
CAS No.
86153-38-0
Chemical Name:
9,11-Dehydro-17α-cyanoMethyl Estradiol
Synonyms
Dinoregin Impurity B;Dinoregin impurity G;9,11-Dehydro-17α-cyanoMethyl Estradiol;9,11-Dehydro-17α-cyanoMethyl Estradiol;Dienogest Impurity 3 (Dienogest EP Impurity G);17α-Cyanomethylestra-1,3,5(10),9(11)-tetraen-3,17β-diol;17a-Cyanomethylestra-1,3,5(10),9(11)-tetraene-3,17b-diol;(17α-Cyanomethylestra-1,3,5(10),9(11)-tetraen-3,17β-diol);3,17-dihydroxyestra-1,3,5(10),9(11)-tetraen-17α-yl]acetonitrile,;[(17β)-3,17-Dihydroxyestra-1,3,5(10),9(11)-tetraen-17-yl]acetonitrile
CBNumber:
CB22695606
Molecular Formula:
C20H23NO2
Molecular Weight:
309.41
MOL File:
86153-38-0.mol
MSDS File:
SDS
Modify Date:
2023/4/23 13:52:06

9,11-Dehydro-17α-cyanoMethyl Estradiol Properties

Melting point 228 - 233°C
Boiling point 551.2±50.0 °C(Predicted)
Density 1.25±0.1 g/cm3(Predicted)
storage temp. -20°C Freezer, Under inert atmosphere
solubility DMSO (Slightly), Methanol (Slightly, Sonicated)
pka 10.37±0.60(Predicted)
form Solid
color White to Off-White

9,11-Dehydro-17α-cyanoMethyl Estradiol Chemical Properties,Uses,Production

Uses

9,11-Dehydro-17α-cyanomethyl Estradiol is a metabolite of progestin dienogest (D441870), and is currently being investigated for progesterone-receptor binding, progestational, antiprogestational, estrogenic and antigonadotropic activities for the inhibition of fertility. It is also being considered a novel treatment for heavy menstrual bleeding.

9,11-Dehydro-17α-cyanoMethyl Estradiol Preparation Products And Raw materials

Raw materials

Preparation Products

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9,11-Dehydro-17α-cyanoMethyl Estradiol 17α-Cyanomethylestra-1,3,5(10),9(11)-tetraen-3,17β-diol 19-Norpregna-1,3,5(10),9(11)-tetraene-21-nitrile, 3,17-dihydroxy-, (17α)- (9CI) Dienogest Impurity 3 (Dienogest EP Impurity G) 17a-Cyanomethylestra-1,3,5(10),9(11)-tetraene-3,17b-diol [(17β)-3,17-Dihydroxyestra-1,3,5(10),9(11)-tetraen-17-yl]acetonitrile 9,11-Dehydro-17α-cyanoMethyl Estradiol (17α-Cyanomethylestra-1,3,5(10),9(11)-tetraen-3,17β-diol) 3,17-dihydroxyestra-1,3,5(10),9(11)-tetraen-17α-yl]acetonitrile, Dinoregin impurity G Dinoregin Impurity B 86153-38-0 Steroids, Pharmaceuticals, Intermediates & Fine Chemicals, Metabolites & Impurities, Drug Analogues