ChemicalBook > Product Catalog >Organic Chemistry >Nitrogen Compounds >(R)-1-[(4-Chlorophenyl)phenylmethyl]piperazine
(R)-1-[(4-Chlorophenyl)phenylmethyl]piperazine
![(R)-1-[(4-Chlorophenyl)phenylmethyl]piperazine Structure](CAS/GIF/300543-56-0.gif)
- CAS No.
- 300543-56-0
- Chemical Name:
- (R)-1-[(4-Chlorophenyl)phenylmethyl]piperazine
- Synonyms
- Levocetirizine Impurity A;Levocetirizine Impurity 2;(R)-Cetirizine EP Impurity A;(R)-1-[(4-Chlorophenyl)phenylmethyl;(R)-1-(p-Chlorobenzhydryl)piperazine;Chlorobenzhydryl Piperazine (F02160);(R)-N-(4-Chlorobenzyl hydryl) piperazine;R(-)-1-[(4-Chlorophenyl)benzyl]piperazine;(-)-1-[(4-CHLOROPHENYL)PHENYLMETHYL]PIPERAZINE;(R)-1-[alpha-(4-Chlorophenyl)benzyl]piperazine
- CBNumber:
- CB2299774
- Molecular Formula:
- C17H19ClN2
- Molecular Weight:
- 286.8
- MOL File:
- 300543-56-0.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/4/26 17:21:34
| Melting point | 91-93oC |
|---|---|
| Boiling point | 409.1±0.0 °C(Predicted) |
| Density | 1.158 |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | Chloroform (Slightly), Dichloromethane (Slightly), Methanol (Slightly) |
| pka | 8.99±0.10(Predicted) |
| form | Solid |
| color | White |
| PH | 9.38 at 25℃ and 10.07g/L |
| Water Solubility | Soluble in chloroform, methanol, and dichloromethane. Slightly soluble in water. |
| InChI | InChI=1/C17H19ClN2/c18-16-8-6-15(7-9-16)17(14-4-2-1-3-5-14)20-12-10-19-11-13-20/h1-9,17,19H,10-13H2/t17-/s3 |
| InChIKey | UZKBSZSTDQSMDR-SCBJWRGWNA-N |
| SMILES | [C@@H](N1CCNCC1)(C1C=CC=CC=1)C1C=CC(Cl)=CC=1 |&1:0,r| |
| CAS DataBase Reference | 300543-56-0 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| HS Code | 2933599550 | |||||||||
| NFPA 704 |
|
(R)-1-[(4-Chlorophenyl)phenylmethyl]piperazine price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ALFA India | ALF-H63722-MD | (R)-1-[alpha-(4-Chlorophenyl)benzyl]piperazine, 97% | 300543-56-0 | 250mg | ₹2806 | 2022-05-26 | Buy |
| ALFA India | ALF-H63722-06 | (R)-1-[alpha-(4-Chlorophenyl)benzyl]piperazine, 97% | 300543-56-0 | 5g | ₹114534 | 2022-05-26 | Buy |
| ALFA India | ALF-H63722-03 | (R)-1-[alpha-(4-Chlorophenyl)benzyl]piperazine, 97% | 300543-56-0 | 1g | ₹9625 | 2022-05-26 | Buy |
(R)-1-[(4-Chlorophenyl)phenylmethyl]piperazine Chemical Properties,Uses,Production
Uses
Intermediate in the production of (R)-Cetirizine (C281106).
Application
(R)-1-[(4-Chlorophenyl)phenylmethyl]piperazine could be used to synthesize a series of novel derivatives. Most of these derivatives significantly affected both allergic asthma and allergic itching. Meanwhile, in the test of allergic itching, five of the 19 compounds have more potent activities than levocetirizine[1].
References
[1] Lisheng Wang. “Design, synthesis, and anti-allergic activities of novel (R)(-)-1-[(4-chlorophenyl)phenyl methyl]piperazine derivatives.” Medicinal Chemistry Research 21 1 (2010): 124–132.
(R)-1-[(4-Chlorophenyl)phenylmethyl]piperazine Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 181)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| ALMELO PRIVATE LIMITED | +91-9100991345 +91-8500807769 | Telangana, India | 114 | 58 | Inquiry |
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| Rui Laboratories Pvt Ltd | 91--9676323459 | Hyderabad, India | 8 | 58 | Inquiry |
| Asiel Chempharma | 91-9920082277 | Maharashtra, India | 119 | 58 | Inquiry |
300543-56-0((R)-1-[(4-Chlorophenyl)phenylmethyl]piperazine)Related Search:
(-)-1-[(4-CHLOROPHENYL)PHENYLMETHYL]PIPERAZINE
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(R)-N-(4-Chlorobenzyl hydryl) piperazine
(R)-1-[(4-chlorophenyl)phenyl methyl] Piperazine (Intermediate of Levocetirizine )
(R)-1-[(4-Chlorophenyl)phenylmethyl]piperazine
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300543-56-0
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