Amino-PEG5-t-butyl ester

Amino-PEG5-t-butyl ester Structure
CAS No.
1446282-18-3
Chemical Name:
Amino-PEG5-t-butyl ester
Synonyms
Amino-PEG5-Boc;Amino-PEG5-COOtBu;NH2-PEG5-C2-COOtBu;NH2-PEG5-CH2CH2COOtBu;H2N-PEG5-CH2CH2COOtBu;Amino-PEG5-t-Bu Ester;Amino-PEG5-t-butyl este;Amino-PEG5-t-butyl ester;tert-butyl 1-amino-3,6,9,12,15-pentaoxaoctadecan-18-oate;4,7,10,13,16-Pentaoxaoctadecanoic acid, 18-amino-, 1,1-dimethylethyl ester
CBNumber:
CB23048678
Molecular Formula:
C17H35NO7
Molecular Weight:
365.46
MOL File:
1446282-18-3.mol
MSDS File:
SDS
Modify Date:
2024/3/22 17:12:53

Amino-PEG5-t-butyl ester Properties

Boiling point 439.1±40.0 °C(Predicted)
Density 1.049±0.06 g/cm3(Predicted)
storage temp. -20°C
solubility Soluble in Water, DMSO, DCM, DMF
pka 8.74±0.10(Predicted)
form viscous liquid
color Light yellowish

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P280-P261
HS Code  2942000090

Amino-PEG5-t-butyl ester Chemical Properties,Uses,Production

Uses

This heterobifunctional, PEGylated crosslinker features an amino group at one end and t-butyl-protected carboxyl group at the other, which can be deprotected with acidic conditions. The hydrophillic PEG linker facilitates solubility in biological applications. Amino-PEG5-t-butyl ester can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC? molecules) for targeted protein degradation.

Amino-PEG5-t-butyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 83)Suppliers
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CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
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Jilin Chinese Academy of Sciences-yanshen Technology +undefined18143011203 China 42057 58 Inquiry
H2N-PEG5-CH2CH2COOtBu NH2-PEG5-CH2CH2COOtBu Amino-PEG5-t-butyl ester 4,7,10,13,16-Pentaoxaoctadecanoic acid, 18-amino-, 1,1-dimethylethyl ester Amino-PEG5-Boc tert-butyl 1-amino-3,6,9,12,15-pentaoxaoctadecan-18-oate Amino-PEG5-COOtBu Amino-PEG5-t-Bu Ester H2N-PEG5-CH2CH2COOtBu/4,7,10,13,16-Pentaoxaoctadecanoic acid, 18-amino-, 1,1-dimethylethyl ester Amino-PEG5-t-butyl este NH2-PEG5-C2-COOtBu tert-butyl 3-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]propanoate 1446282-18-3 peg