2-(3-cyano-4-propoxyphenyl)-4-methylthiazole-5-carboxylic acid

2-(3-cyano-4-propoxyphenyl)-4-methylthiazole-5-carboxylic acid Structure
CAS No.
1530308-87-2
Chemical Name:
2-(3-cyano-4-propoxyphenyl)-4-methylthiazole-5-carboxylic acid
Synonyms
Febuxostat-20;Desmethylfebuxostat;Febuxostat Impurity U;Febuxostat impurities 16;Febuxostat Impurity 22 (I);2-(3-cyano-4-propoxyphenyl);Febuxostat Propyl Ether Acid;Febuxostat Related Compound B;Febuxostat Propyl Ether Acid Impurity;Febuxostat t-Butyl Ether Acid Impurity
CBNumber:
CB23146800
Molecular Formula:
C15H14N2O3S
Molecular Weight:
302.35
MOL File:
1530308-87-2.mol
Modify Date:
2024/7/10 17:45:06

2-(3-cyano-4-propoxyphenyl)-4-methylthiazole-5-carboxylic acid Properties

Boiling point 537.1±60.0 °C(Predicted)
Density 1.34±0.1 g/cm3(Predicted)
solubility DMSO (Slightly), Methanol (Slightly)
pka 2.49±0.10(Predicted)
form Solid
color Off-White to Pale Yellow

2-(3-cyano-4-propoxyphenyl)-4-methylthiazole-5-carboxylic acid Chemical Properties,Uses,Production

Uses

O-Desisobutyl-O-n-propyl Febuxostat is an impurity of the drug Febuxostat(F229000).

2-(3-cyano-4-propoxyphenyl)-4-methylthiazole-5-carboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

2-(3-cyano-4-propoxyphenyl)-4-methylthiazole-5-carboxylic acid 2-(3-Cyano-4-propoxyphenyl)-4-methyl-5-thiazolecarboxylic acid Febuxostat Propyl Ether Acid Impurity 5-Thiazolecarboxylic acid, 2-(3-cyano-4-propoxyphenyl)-4-methyl- Febuxostat Related Compound B Desmethylfebuxostat Febuxostat impurities 16 Febuxostat Impurity 22 (I) Febuxostat-20 Febuxostat Impurity 25/Febuxostat N-Propyl Ether Acid Impurity/2-(3-cyano-4-propoxyphenyl)-4-methylthiazole-5-carboxylic acid 2-(3-cyano-4-propoxyphenyl) Febuxostat n-Propyl Ether Acid Impurity Febuxostat t-Butyl Ether Acid Impurity Febuxostat Impurity U Febuxostat Propyl Ether Acid 1530308-87-2