ChemicalBook > Product Catalog >Chemical Reagents >Organic reagents >Aromatic ketones >2',4',6'-Trihydroxyacetophenone monohydrate

2',4',6'-Trihydroxyacetophenone monohydrate

2',4',6'-Trihydroxyacetophenone monohydrate Structure
CAS No.
480-66-0
Chemical Name:
2',4',6'-Trihydroxyacetophenone monohydrate
Synonyms
THAP;Phloracetophenone;PHLOROACETOPHENONE;Monoacetylphloroglucinol;2-Acetylphloroglucinol hydrate;2',4',6'-TRIHYDROXYACETOPHENONE;2,4,6-trihydroxylacetophenone monohydrate;NSC 54927;Phloracetophene;Acetophloroglucine
CBNumber:
CB2333652
Molecular Formula:
C8H8O4
Molecular Weight:
168.15
MOL File:
480-66-0.mol
MSDS File:
SDS
Modify Date:
2024/4/1 18:08:31

2',4',6'-Trihydroxyacetophenone monohydrate Properties

Melting point 219-221 °C(lit.)
Boiling point 257.07°C (rough estimate)
Density 1.3037 (rough estimate)
refractive index 1.5090 (estimate)
storage temp. Store below +30°C.
solubility DMSO (Sparingly), Ethanol (Slightly), Methanol (Slightly), Water (Very Slightly,
form Powder
pka 7.76±0.23(Predicted)
color light yellow
Water Solubility Soluble in water.
BRN 1911197
Stability Stable under recommended storage conditions., Stable Under Recommended Storage C
LogP 1.472 (est)
CAS DataBase Reference 480-66-0(CAS DataBase Reference)
NIST Chemistry Reference Ethanone, 1-(2,4,6-trihydroxyphenyl)-(480-66-0)
EPA Substance Registry System Ethanone, 1-(2,4,6-trihydroxyphenyl)- (480-66-0)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H303-H315-H319-H335
Precautionary statements  P280g-P261-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36-24/25
WGK Germany  3
RTECS  AN0528000
TSCA  Yes
HazardClass  IRRITANT
HS Code  29145000
NFPA 704
0
2 0

2',4',6'-Trihydroxyacetophenone monohydrate price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ALFA India ALF-L04156-14 2',4',6'-Trihydroxyacetophenone hydrate, 98+% 480-66-0 25g ₹11436 2022-05-26 Buy
ALFA India ALF-L04156-06 2',4',6'-Trihydroxyacetophenone hydrate, 98+% 480-66-0 5g ₹4559 2022-05-26 Buy
TCI Chemicals (India) T1888 2',4',6'-Trihydroxyacetophenone Monohydrate min. 98.0 % 480-66-0 5G ₹3800 2022-05-26 Buy
TCI Chemicals (India) T1888 2',4',6'-Trihydroxyacetophenone Monohydrate min. 98.0 % 480-66-0 25G ₹13400 2022-05-26 Buy
Product number Packaging Price Buy
ALF-L04156-14 25g ₹11436 Buy
ALF-L04156-06 5g ₹4559 Buy
T1888 5G ₹3800 Buy
T1888 25G ₹13400 Buy

2',4',6'-Trihydroxyacetophenone monohydrate Chemical Properties,Uses,Production

Chemical Properties

Light Brown Solid

Preparation

Preparation by reaction of acetic anhydride on phloroglucinol,
with concentrated sulfuric acid at 130° (70%)
with boron trifluoride at 10° (62.5–68%)
with zinc chloride at 145–150° (50%)
with Amberlite IR-120 or Zeokarb 225 (cation exchange resins, sulfonic acid type) at 160° (39%).

Definition

ChEBI: A benzenetriol that is acetophenone in which the hydrogens at positions 2, 4, and 6 on the phenyl group are replaced by hydroxy groups. It is used as a matrix in matrix-assisted laser desorption/ionization (MALDI) mass spectrometry for the analysis of acid c glycans and glycopeptides.

Purification Methods

Crystallise the ketone from hot H2O (35mL/g). [Beilstein 8 IV 2729.]

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2',4',6'-Trihydroxyacetophenone monohydrate Phloroacetophenone monohydrate 2',4',6'-Trihydroxyacetophenone (monohydrate/anhydrous) 2',4',6'-Trihydroxyacetophenone hydrate, 98+% 1-(2,4,6-TRIHYDROXYPHENYL)-ETHANONE Acetophenone,2’,4’,6’-trihydroxy- Acetophloroglucine Acetylphloroglucinol Ethanone,1-(2,4,6-trihydroxyphenyl)- Phloracetophene Phloroacetophenonehydrate 2,4,6-TRIHYDROXYACETOPHENONE(PHLOROACETOPHENONE) 2,4,6-Trihydroxyaetcophenone 2,4,6-TRIHYDROXYACETOPHENONE MONOHYDRATE, PGE. WITH 10X10 MG 2,4,6-TRIHYDROXYLACETOPHENONE NSC 54927 2',4',6'-Trihydroxyacetophenone,98% 2-Acetylphloroglucinol, THAP 1-(2,4,6-tTihydroxyphenyl)ethanone 2,4,6-Trihydroxy-1-acetylbenzene Methyl-(2,4,6-trihydroxyphenyl) ketone 2',4',6'-Trihydroxya 1-(2,4,6-Trihydroxyphenyl)ethan-1-one, 2-Acetylbenzene-1,3,5-triol 1-(2,4-dihydroxyphenyl)-2-hydroxyethan-1-one 2-Acetylphloroglucinol Phloroacetophenone 1-(2,4,6-trihydroxyphenyl)ethanone hydrate 2',4', 6'-Trihydroxyacetophenone Monohydrat 2',4',6'-trihydroxyacetopheMone Acetophenone, 2',4',6'-trihydroxy- (8CI) 1-(2,4,6-trihydroxyphenyl)-ethanon 2,4,6-Trihydroxyacetophenon 2,4,6-TrihydroxyacetophenonMonohydrat 2,4,6-trihyroxyacetophenone 2-Acetyl-1,3,5-trihydroxybenzene 2-Acetylphloroglucin Acetophenone, 2',4',6'-trihydroxy- 6'-Trihydroxyacetophenone 2-(2,4-dihydroxyphenyl)-2-hydroxy-1-phenylethanone JR-13799, 1-(2,4,6-Trihydroxyphenyl)ethanone hydrate, 98% 2,4,6-Trihydroxyacetophenone.H2O 2',4',67-TRIHYDROXYACETOPHENONE MONOHYDR Phloroglucinol Acetyl 2-Acetylphloroglucinol hydrate THAP 2',4',6'-TRIHYDROXYACETOPHENONE Phloracetophenone PHLOROACETOPHENONE Monoacetylphloroglucinol 2,4,6-trihydroxylacetophenone monohydrate Phloracetophenone/2',4',6'-Trihydroxyacetophenone 1-(2,4,6-trihydroxyphenyl)ethan-1-one 2',4',6'-Trihydroxyacetophenone 2',4',6'-Trihydroxyacetophenon 480-66-0 C8H8O4xH2O HO3C6H2COCH3H2O Ketones C7 to C8