Dde Biotin-PEG4-Picolyl Azide
![Dde Biotin-PEG4-Picolyl Azide Structure](CAS/20211123/GIF/2055048-42-3.gif)
- CAS No.
- 2055048-42-3
- Chemical Name:
- Dde Biotin-PEG4-Picolyl Azide
- Synonyms
- Dde Biotin-PEG4-Picolyl Azide;Dde Biotin-PEG4-Picolyl azide Dde
- CBNumber:
- CB23363904
- Molecular Formula:
- C38H57N9O9S
- Molecular Weight:
- 815.99
- MOL File:
- 2055048-42-3.mol
- Modify Date:
- 2024/3/21 13:23:50
Dde Biotin-PEG4-Picolyl Azide Chemical Properties,Uses,Production
Uses
Dde biotin picolyl azide is a unique alkyne-reactive, cleavable biotin probe that allows for release of the captured biomolecules from streptavidin under mild conditions. This reagent contains a biotin moiety linked to a picolyl azide moiety through a spacer arm containing a hydrazine-cleavable Dde moiety. Captured biomolecules can be efficiently released, typically >90% with 2% hydrazine in aqueous media.
Dde biotin picolyl azide incorporates a copper-chelating motif that dramatically accelerates the Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC) reaction under conditions relevant to biomolecular labeling. Discovery of azides with an internal Cu(I)-chelating motif greatly enhances the utility of the CuAAC reaction for various applications. Some examples are monitoring the dynamic glycan biosynthesis in living organisms; sensitive detection of metabolically-labeled proteins, DNAs, and RNAs; and many other applications where rate acceleration and reduced cell toxicity are highly desirable.
Dde Biotin-PEG4-Picolyl Azide Preparation Products And Raw materials
Raw materials
Preparation Products
Dde Biotin-PEG4-Picolyl Azide Suppliers
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 19892 | 58 | Inquiry |
Alfa Chemistry | United States | 24072 | 58 | Inquiry | |
Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | China | 49739 | 58 | Inquiry |
Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | China | 42057 | 58 | Inquiry |
Xian confluore Biological Technology Co., Ltd. | +86-15680926068 +86-15680926068 | China | 2996 | 58 | Inquiry |
Xi'an Confluore Biological Technology Co., Ltd. | +86-156-80926068 +86-15680926068 | China | 4824 | 58 | Inquiry |
Shanghai Easy CDMO Co.,Ltd | 021-61734564 | China | 10010 | 58 | Inquiry |
Jilin Chinese Academy of Sciences-yanshen Technology | 18143011203 | China | 41844 | 58 | Inquiry |
Shanghai Haohong Scientific Co., Ltd. | 400-400-8210725 | China | 39990 | 58 | Inquiry |
Hangzhou Taorui Biotechnology Co., Ltd | 4000-360-990 15268198094 | China | 2763 | 58 | Inquiry |