DADEPYLIPQQG
- CAS No.
- Chemical Name:
- DADEPYLIPQQG
- Synonyms
- EGFR;DADEPYLIPQQG;EGFR (988-998);DADEY(PO3)LIPQQG;Mouse Anti-EGFR antibody;Rat EGFR Protein, His Tag;Mouse EGFR Protein, Fc Tag;Human EGFR Protein, Fc Tag;Mouse EGFR Protein, His Tag;Human EGFR Protein, His Tag
- CBNumber:
- CB2770154
- Molecular Formula:
- C54H82N13O24P
- Molecular Weight:
- 1328.28
- MOL File:
- Mol file
- Modify Date:
- 2023/4/23 13:52:06
DADEPYLIPQQG price More Price(2)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | E3641 | Epidermal Growth Factor Receptor human buffered aqueous glycerol solution, 5,000-30,000?units/mg protein (Lowry) | 500UNITS | ₹64776.8 | 2022-06-14 | Buy | |
| Sigma-Aldrich(India) | E2645 | Epidermal Growth Factor Receptor human lyophilized powder, ≥15,000?units/mg protein (Bradford) | 500UNITS | ₹52252.28 | 2022-06-14 | Buy |
DADEPYLIPQQG Chemical Properties,Uses,Production
General Description
Epidermal growth factor receptor (EGFR) belongs to a family of cell surface receptors called receptor tyrosine kinases (RTKs), and is also the most studied member of this family. It is made up of an ectodomain (ECD), which contains four subdomains called DI-DIV, a transmembrane region, and a cytoplasmic tyrosine kinase domain (TKD). Binding of the ligand induces conformational changes in the ECD, which leads to the dimerization of EGFR. This results in the activation of the TKD, and the subsequent signal transduction. This receptor has a molecular weight of ～178kDa.
Biochem/physiol Actions
EGF exerts its actions by binding to the EGF receptor (EGFR), a 170 kDa glycoprotein having EGF-activated protein tyrosine kinase activity. Even in the absence of EGF-like ligands, EGFR can participate in cellular responses elicited by several other stimuli. High levels of EGFR are expressed in approximately one third of human epithelial tumors, and in the cancers of the bladder, breast or lung that have poor clinical prognosis, hence the interest in targeting EGFR.
DADEPYLIPQQG Preparation Products And Raw materials
Raw materials
Preparation Products
DADEPYLIPQQG Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| AnaSpec, Inc. | 800 452 5530 | United States | 4871 | 77 | Inquiry |
| EMD Biosciences, Inc. | 858 450 5500 | United States | 6529 | 66 | Inquiry |
| VWR International | 800 932 5000 | United Kingdom | 6548 | 82 | Inquiry |
| MP Biomedicals, Inc. | 949 833 2500 | United States | 6561 | 81 | Inquiry |
| GL Biochem (Shanghai) Ltd | 21-61263452 13641803416 | China | 9981 | 64 | Inquiry |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | China | 15839 | 69 | Inquiry |
| Apollo Scientific Ltd. | 44 161 406 0505 | United Kingdom | 6084 | 88 | Inquiry |
| Riedel-de Haen AG | 800 558-9160 | United States | 6773 | 87 | Inquiry |
| Guangzhou Weijia Technology Co., Ltd. | 020-84224925 18300190102 | CHINA | 6748 | 58 | Inquiry |
| Xi Shi Biotechnology (Shanghai) Co., Ltd. | 021-50781653 13761860314 | CHINA | 2590 | 58 | Inquiry |