8-(4-Chlorobutyl)-8-azaspiro[4.5]decane-7,9-dione

8-(4-Chlorobutyl)-8-azaspiro[4.5]decane-7,9-dione Structure
CAS No.
21098-11-3
Chemical Name:
8-(4-Chlorobutyl)-8-azaspiro[4.5]decane-7,9-dione
Synonyms
IMPURITY-L;Buspirone EP Impurity L;Buspirone USP Related Compound L;8-(4-Chlorobutyl)-8-azaspiro[4.5]-d;Buspirone Hydrochloride EP Impurity L;Buspirone Impurity 12(Buspirone EP Impurity L);8-(4-Chlorobutyl)-8-azaspiro[4.5]decane-7,9-dione;8-Azaspiro[4.5]decane-7,9-dione, 8-(4-chlorobutyl)-;Buspirone EP Impurity L/ Buspirone Related Compund L;8-(4-Chlorobutyl)-8-azaspiro[4.5]decane-7,9-dione (Buspirone Impurity)
CBNumber:
CB32695577
Molecular Formula:
C13H20ClNO2
Molecular Weight:
257.76
MOL File:
21098-11-3.mol
MSDS File:
SDS
Modify Date:
2023/5/4 15:12:35

8-(4-Chlorobutyl)-8-azaspiro[4.5]decane-7,9-dione Properties

Boiling point 429.4±28.0 °C(Predicted)
Density 1.18±0.1 g/cm3(Predicted)
storage temp. Refrigerator
solubility Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form Oil
pka -1.48±0.20(Predicted)
color Colourless

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS08,GHS07
Signal word  Warning
Hazard statements  H302-H341
Precautionary statements  P264-P270-P301+P312-P330-P501-P201-P202-P281-P308+P313-P405-P501
HS Code  2933599550

8-(4-Chlorobutyl)-8-azaspiro[4.5]decane-7,9-dione Chemical Properties,Uses,Production

Uses

8-(4-Chlorobutyl)-8-azaspiro[4.5]decane-7,9-dione is an impurity of Buspirone (B689850), an non-benzodiazepine anxiolytic; 5-hydroxytryptamine (5-HT1) receptor agonist.

8-(4-Chlorobutyl)-8-azaspiro[4.5]decane-7,9-dione Preparation Products And Raw materials

Raw materials

Preparation Products

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Buspirone EP Impurity L Buspirone Impurity 12(Buspirone EP Impurity L) 8-(4-Chlorobutyl)-8-azaspiro[4.5]-d 8-Azaspiro[4.5]decane-7,9-dione, 8-(4-chlorobutyl)- Buspirone EP Impurity L/ Buspirone Related Compund L Buspirone Related Compound L (8-(4-Chlorobutyl)-8-azaspiro[4.5]decane-7,9-dione) (1078824) Buspirone USP Related Compound L 8-(4-Chlorobutyl)-8-azaspiro[4.5]decane-7,9-dione (Buspirone Impurity) Buspirone Hydrochloride EP Impurity L IMPURITY-L 8-(4-Chlorobutyl)-8-azaspiro[4.5]decane-7,9-dione 21098-11-3 Heterocycles, Impurities, Pharmaceuticals, Intermediates & Fine Chemicals