(4AR,9AS)-(+)-4A-AMINO-1,2,3,4,4A,9A-HEXAHYDRO-4AH-FLUORENE, HCL
- CAS No.
- Chemical Name:
- (4AR,9AS)-(+)-4A-AMINO-1,2,3,4,4A,9A-HEXAHYDRO-4AH-FLUORENE, HCL
- Synonyms
- AHF;F8B;F8C;FVIII;Anti-AHF;Anti-F8C;Anti-F8B;Anti-HEMA;Anti-FVIII;Anti-DXS1253E
- CBNumber:
- CB3286186
- Molecular Formula:
- C13H18ClN
- Molecular Weight:
- 223.74
- MOL File:
- Mol file
(4AR,9AS)-(+)-4A-AMINO-1,2,3,4,4A,9A-HEXAHYDRO-4AH-FLUORENE, HCL Chemical Properties,Uses,Production
Uses
Antihemophilic factor is a protein that converts prothrombin to thrombin, and replaces a deficit of endogenic hemophilic factor. It is synthesized by processing human plasma. It is used to treat classic hemophilia A and to stop bleeding.
General Description
This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder. (provided by RefSeq)
(4AR,9AS)-(+)-4A-AMINO-1,2,3,4,4A,9A-HEXAHYDRO-4AH-FLUORENE, HCL Preparation Products And Raw materials
Raw materials
Preparation Products
(4AR,9AS)-(+)-4A-AMINO-1,2,3,4,4A,9A-HEXAHYDRO-4AH-FLUORENE, HCL Suppliers
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