beta-D-Ribofuranose 1-acetate 2,3,5-tribenzoate
![beta-D-Ribofuranose 1-acetate 2,3,5-tribenzoate Structure](/CAS/20180906/GIF/6974-32-9.gif)
- CAS No.
- 6974-32-9
- Chemical Name:
- beta-D-Ribofuranose 1-acetate 2,3,5-tribenzoate
- Synonyms
- 1-O-Acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose;ABR;NSC 23349;1-Acetyl-2;1-O-AcetyL;B-D-RIBOFURANOSE;-β-D-ribofuranose;-2,3,5-tri-O-benzoyL;ACETYLTRIBENZOYLRIBOSE;RibofuranoseAcetateTribenzoate
- CBNumber:
- CB3292813
- Molecular Formula:
- C28H24O9
- Molecular Weight:
- 504.48
- MOL File:
- 6974-32-9.mol
- Modify Date:
- 2023/11/23 16:42:02
Melting point | 128-130 °C |
---|---|
Boiling point | 621.0±55.0 °C(Predicted) |
alpha | 24.4 º (c=1, pyridine) |
Density | 1.35±0.1 g/cm3(Predicted) |
refractive index | 24 ° (C=1, Pyridine) |
storage temp. | Sealed in dry,Room Temperature |
solubility | Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly, Sonicated), |
form | Liquid |
color | Clear slightly yellow or greenish to brown |
optical activity | [α]20/D +24.3°, c = 1 in pyridine |
BRN | 100243 |
InChIKey | GCZABPLTDYVJMP-CBUXHAPBSA-N |
SMILES | C(OC)(=O)C1=CC=CC=C1[C@@H]1[C@@H](OC(=O)C2=CC=CC=C2)[C@@H](OC(=O)C2=CC=CC=C2)[C@H](OC(C)=O)O1 |&1:10,11,21,31,r| |
CAS DataBase Reference | 6974-32-9(CAS DataBase Reference) |
EPA Substance Registry System | .beta.-D-Ribofuranose, 1-acetate 2,3,5-tribenzoate (6974-32-9) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H315-H319-H335 | |||||||||
Precautionary statements | P261-P305+P351+P338 | |||||||||
Hazard Codes | Xi | |||||||||
Risk Statements | 36/38 | |||||||||
Safety Statements | 22-24/25-37/39-26 | |||||||||
WGK Germany | 3 | |||||||||
TSCA | Yes | |||||||||
HS Code | 29400090 | |||||||||
NFPA 704 |
|
beta-D-Ribofuranose 1-acetate 2,3,5-tribenzoate price More Price(9)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | 159018 | β-D-Ribofuranose 1-acetate 2,3,5-tribenzoate 98% | 6974-32-9 | 1G | ₹1905.2 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | PHR3472 | Azacitidine Related Compound B certified reference material, pharmaceutical secondary standard | 6974-32-9 | 30MG | ₹45421.7 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 159018 | β-D-Ribofuranose 1-acetate 2,3,5-tribenzoate 98% | 6974-32-9 | 10G | ₹5022.8 | 2022-06-14 | Buy |
ALFA India | ALF-L14302-06 | 1-O-Acetyl-2,3,5-tri-O-benzoyl-beta-D-ribofuranose, 98% | 6974-32-9 | 5g | ₹3075 | 2022-05-26 | Buy |
ALFA India | ALF-L14302-03 | 1-O-Acetyl-2,3,5-tri-O-benzoyl-beta-D-ribofuranose, 98% | 6974-32-9 | 1g | ₹1816 | 2022-05-26 | Buy |
beta-D-Ribofuranose 1-acetate 2,3,5-tribenzoate Chemical Properties,Uses,Production
Chemical Properties
white to light yellow crystal powde
Uses
An inhibitor of neutrophil-keyhole limpet hemocyanin adhesion
Application
Beta-D-Ribofuranose 1-acetate 2,3,5-tribenzoate, also known as 1-O-Acetyl-2,3,5-tri-O-benzoyl-beta-D-ribofuranose, is a ribose-derived compound used in nucleoside synthesis.
Synthesis
Rac-(2R,3R,4R,5R)-2-((benzoyloxy)methyl)-5-hydroxytetrahydrofuran-3,4-diyl dibenzoate was dissolved in dry pyridine, and the solution was slowly added dropwise with acetic anhydride in an ice water bath, then stirred for 30 minutes. Then, the ice water bath was removed, and the solution was stirred at room temperature for 7 hours and then heated to 40°C. This temperature was kept for an hour. The solution was added with broken ice and then stirred until the broken ice melted. The reaction solution was poured into ice water and extracted with chloroform. The organic layer was washed sequentially with ice water, pre-cooled sulfuric acid, and saturated sodium bicarbonate until the water layer showed weak alkaline, then washed with ice water until the water layer showed neutral, dried over anhydrous sodium sulfate for more than 4 hours, and then drawn off under reduced pressure, to obtain the light yellow syrup-like beta-D-Ribofuranose 1-acetate 2,3,5-tribenzoate (92.1%).
Purification Methods
Recrystallise it from EtOH or isoPrOH. [Helv Chim Acta 42 1171 1959, NMR: J Org Chem 33 1799 1968, IR: Chem Pharm Bull Jpn 11 188 1963, Beilstein 17/6 V 213.]
beta-D-Ribofuranose 1-acetate 2,3,5-tribenzoate Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
Louis Pharmaceuticals Pvt Ltd | +91-8498087900 +91-8498087900 | Telangana, India | 23 | 58 | Inquiry |
CLEANCHEM LABORATORIES LLP | +91-9951015911 +91-9951015911 | Mumbai, India | 281 | 58 | Inquiry |
Suven Pharmaceuticals Limited | +91-91-40-23541142 +91-4023541142 | Telangana, India | 218 | 58 | Inquiry |
Vepan Pharmatech Pvt Ltd | +91-9908788828 +91-9966094448 | Telangana, India | 72 | 58 | Inquiry |
ChemGenes India Pvt Ltd | +91-8687421036 +91-8687421036 | Uttar Pradesh, India | 16 | 58 | Inquiry |
OCEAN TRADING CORPORATION | +91(22) 24921669 | New Delhi, India | 6211 | 58 | Inquiry |
CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
Manus Aktteva | +91 (79) 6512-3395 | New Delhi, India | 581 | 34 | Inquiry |
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
Supplier | Advantage |
---|---|
Louis Pharmaceuticals Pvt Ltd | 58 |
CLEANCHEM LABORATORIES LLP | 58 |
Suven Pharmaceuticals Limited | 58 |
Vepan Pharmatech Pvt Ltd | 58 |
ChemGenes India Pvt Ltd | 58 |
OCEAN TRADING CORPORATION | 58 |
CHEMSWORTH | 30 |
Manus Aktteva | 34 |
CLEARSYNTH LABS LTD. | 58 |
A.J Chemicals | 58 |
beta-D-Ribofuranose 1-acetate 2,3,5-tribenzoate Spectrum
6974-32-9(beta-D-Ribofuranose 1-acetate 2,3,5-tribenzoate)Related Search:
1of4
chevron_right