Obeticholic Acid Impurity 2

Obeticholic Acid Impurity 2 Structure
CAS No.
915038-27-6
Chemical Name:
Obeticholic Acid Impurity 2
Synonyms
Obeticholic Impurity 2;6-epi-Obeticholic Acid;Obeticholic Acid 6-Epimer;Obeticholic acid Impurity 03;Obeticholic Acid impurity 06;Cholan-24-oic acid, 6-ethyl-3,7-dihydroxy-, (3α,5β,6β,7α)-;(3alpha,5beta,6beta,7alpha)-6-Ethyl-3,7-dihydroxycholan-24-oic acid;Obeticholic Acid Impurity 5/6-epi-Obeticholic Acid/(3α,5β,6β,7α)-6-Ethyl-3,7-dihydroxycholan-24-oic Acid;(R)-4-((3R,5S,6S,7R,10S,13R)-6-ethyl-3,7-dihydroxy-10,13-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid
CBNumber:
CB33049304
Molecular Formula:
C26H44O4
Molecular Weight:
420.63
MOL File:
915038-27-6.mol
Modify Date:
2022/12/21 16:56:50

Obeticholic Acid Impurity 2 Properties

Boiling point 562.9±25.0 °C(Predicted)
Density 1.091±0.06 g/cm3(Predicted)
pka 4.76±0.10(Predicted)

Obeticholic Acid Impurity 2 Chemical Properties,Uses,Production

Uses

6-epi-Obeticholic Acid is obtained from Nutriacholic Acid Methyl Ester (N925555) which is the methyl ester of Nutriacholic Acid (N925550), a derivative of Lithocholic Acid (L469180). The Lithocholic Acid (L469180) is a cholic acid derivative as TGR5 modulator. Impurity in the synthesis of Obeticholic Acid (E899810).

Obeticholic Acid Impurity 2 Preparation Products And Raw materials

Raw materials

Preparation Products

(R)-4-((3R,5S,6S,7R,10S,13R)-6-ethyl-3,7-dihydroxy-10,13-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid Obeticholic Acid Impurity 5/6-epi-Obeticholic Acid/(3α,5β,6β,7α)-6-Ethyl-3,7-dihydroxycholan-24-oic Acid Obeticholic Acid 6-Epimer Obeticholic acid Impurity 03 (3alpha,5beta,6beta,7alpha)-6-Ethyl-3,7-dihydroxycholan-24-oic acid 6-epi-Obeticholic Acid Obeticholic Impurity 2 Cholan-24-oic acid, 6-ethyl-3,7-dihydroxy-, (3α,5β,6β,7α)- Obeticholic Acid impurity 06 915038-27-6