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ORM-15341

ORM-15341 Structure
CAS No.
1297537-33-7
Chemical Name:
ORM-15341
Synonyms
ORM-15341;Ketodarolutamide;Dantrolene Impurity 8;Darolutamide Impurity 2;ORM-15341(Ketodarolutamide);5-Acetyl-N-[(1S)-2-[3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-...;3-acetyl-N-[(2S)-1-[3-(3-chloro-4-cyanophenyl)pyrazol-1-yl]propan-2-yl]-1H-pyrazole-5-carboxamide;5-Acetyl-N-[(1S)-2-[3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl]-1-methylethyl]-1H-pyrazole-3-carboxa;(S)-5-acetyl-N-(1-(3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl)propan-2-yl)-1H-pyrazole-3-carboxamide;(S)-3-acetyl-N-(1-(3-(3-chloro-4-cyano-phenyl)-1H-pyrazol-1-yl)propan-2-yl)-1H-pyrazole-5-carboxamide
CBNumber:
CB33053921
Molecular Formula:
C19H17ClN6O2
Molecular Weight:
396.83
MOL File:
1297537-33-7.mol
Modify Date:
2024/10/28 23:16:16
Request For Quotation

ORM-15341 Properties

Melting point 210 - 212?C
Boiling point 714.7±60.0 °C(Predicted)
Density 1.41±0.1 g/cm3(Predicted)
storage temp. -20°C Freezer, Under inert atmosphere
solubility DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
pka 8.70±0.10(Predicted)
form Solid
color White to Off-White

ORM-15341 Chemical Properties,Uses,Production

Uses

ORM-15341 is a metabolite of Darolutamide. Darolutamide is a potent androgen receptor antagonist with strong efficacy in prostate cancer models.

ORM-15341 Preparation Products And Raw materials

Raw materials

ethyl 5-acetyl-1H-pyrazole-3-carboxylate 2-Chloro-4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)benzonitrile 2-Chloro-4-(1h-pyrazol-5-yl)benzonitrile hydrochloride 2-[2-[(E)-2-[4-(dimethylamino)phenyl]ethenyl]-6-methylpyran-4-ylidene]propanedinitrile 4-Bromo-2-chlorobenzonitrile
(S)-4-(1-(2-aminopropyl)-1H-pyrazol-3-yl)-2-chlorobenzonitrile 2-chloro-4-(1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazol-5-yl)benzonitrile 2-Chloro-4-(1H-Pyrazol-5-Yl)Benzonitrile CHEMBRDG-BB 4005123 Isopropyl alcohol
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Preparation Products

ORM-15341 Suppliers

Global( 111)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6257 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6739 58 Inquiry
SynZeal Research Pvt Ltd +1 226-802-2078 Gujarat, India 6514 58 Inquiry
Pharma Affiliates 172-5066494 Haryana, India 6754 58 Inquiry
Hebei Xinsheng New Material Technology Co., LTD. +86-16632316109 China 1085 58 Inquiry
Henan Tianfu Chemical Co.,Ltd. +86-0371-55170693 +86-19937530512 China 21634 55 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32951 60 Inquiry
Jinan Carbotang Biotech Co.,Ltd. +8615866703830 China 8497 58 Inquiry
BOC Sciences +1-631-485-4226 United States 19553 58 Inquiry
SHANGHAI T&W PHARMACEUTICAL CO., LTD. +86-021-61551413 +8618813727289 China 5738 58 Inquiry
Supplier Advantage
CLEARSYNTH LABS LTD. 58
Pharmaffiliates Analytics and Synthetics P. Ltd 58
SynZeal Research Pvt Ltd 58
Pharma Affiliates 58
Hebei Xinsheng New Material Technology Co., LTD. 58
Henan Tianfu Chemical Co.,Ltd. 55
ATK CHEMICAL COMPANY LIMITED 60
Jinan Carbotang Biotech Co.,Ltd. 58
BOC Sciences 58
SHANGHAI T&W PHARMACEUTICAL CO., LTD. 58

ORM-15341 Spectrum

ORM-15341(1297537-33-7)1HNMR
ORM-15341 (S)-5-acetyl-N-(1-(3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl)propan-2-yl)-1H-pyrazole-3-carboxamide 5-Acetyl-N-[(1S)-2-[3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl]-1-methylethyl]-1H-Pyrazole-3-carboxamide (S)-3-acetyl-N-(1-(3-(3-chloro-4-cyano-phenyl)-1H-pyrazol-1-yl)propan-2-yl)-1H-pyrazole-5-carboxamide 1H-Pyrazole-3-carboxamide, 5-acetyl-N-[(1S)-2-[3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl]-1-methylethyl]- Ketodarolutamide ORM-15341(Ketodarolutamide) 5-Acetyl-N-[(1S)-2-[3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-... 5-Acetyl-N-[(1S)-2-[3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl]-1-methylethyl]-1H-pyrazole-3-carboxa Darolutamide Impurity 2 3-acetyl-N-[(2S)-1-[3-(3-chloro-4-cyanophenyl)pyrazol-1-yl]propan-2-yl]-1H-pyrazole-5-carboxamide Dantrolene Impurity 8 1297537-33-7