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Delpazolid

Delpazolid Structure
CAS No.
1219707-39-7
Chemical Name:
Delpazolid
Synonyms
CS-2617;Delpazolid;LCB01-0371;Delpazolid (LCB01-0371);Antibiotic,Delpazolid,inhibit,Bacterial,Inhibitor;DELPAZOLID; LCB01-0371; LCB 01-0371; LCB-01-0371; LCB010371; LCB 010371; LCB-010371;(R)-3-(3-fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4(1H)-yl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one;(5R)-3-[4-(5,6-Dihydro-1-methyl-1,2,4-triazin-4(1H)-yl)-3-fluorophenyl]-5-(hydroxymethyl)-2-oxazolidinone;2-Oxazolidinone, 3-[4-(5,6-dihydro-1-methyl-1,2,4-triazin-4(1H)-yl)-3-fluorophenyl]-5-(hydroxymethyl)-, (5R)-;(5R)-3-[3-fluoro-4-(1-methyl-1,4,5,6-tetrahydro-1,2, 4-triazin-4-yl)phenyl]-5-(hydroxymethyl)-1,3-oxazo lidin-2-one
CBNumber:
CB33357946
Molecular Formula:
C14H17FN4O3
Molecular Weight:
308.31
MOL File:
1219707-39-7.mol
Modify Date:
2024/7/2 8:55:06
Request For Quotation

Delpazolid Properties

Boiling point 481.8±55.0 °C(Predicted)
Density 1.44±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO:30.0(Max Conc. mg/mL);97.3(Max Conc. mM)
form A crystalline solid
pka 14.05±0.10(Predicted)
color White to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501

Delpazolid Chemical Properties,Uses,Production

Description

Delpazolid is an oxazolidinone antibiotic. It is active against a wide range of Gram-positive bacterial clinical isolates, including resistant strains of several species, such as methicillin-resistant S. aureus (MRSA), methicillin-resistant coagulase-negative staphylococci (MRCNS), and penicillin-resistant S. pneumoniae (MICs = 0.125-4 μg/ml). Delpazolid increases survival in mouse models of systemic MRSA, E. faecalis, S. pneumoniae, and H. influenzae infection (ED50s = 2.96, 4.53, 2.28, and 9.96 mg/kg, respectively).

Delpazolid Preparation Products And Raw materials

Raw materials

ethyl (3-fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4(1H)-yl)phenyl)carbamate(WXG00214) 2-fluoro-N-(2-(1-methylhydrazinyl)ethyl)-4-nitroaniline(WXG00212) 3-FLUORO-4-(1-METHYL-5,6-DIHYDRO-1H-[1,2,4]TRIAZIN-4-YL)-PHENYLAMINE(WXG00213) 1334167-59-7 4-(2-fluoro-4-nitrophenyl)-1-methyl-1,4,5,6-tetrahydro-1,2,4-triazine
(R)-Glycidyl butyrate Formaldehyde 3,4-Difluoronitrobenzene
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Preparation Products

Delpazolid Suppliers

Global( 69)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29826 58 Inquiry
Baoji Guokang Healthchem co.,ltd +8615604608665 15604608665 CHINA 9427 58 Inquiry
Guangzhou TongYi biochemistry technology Co.,LTD +8613073028829 China 2996 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 United States 19973 58 Inquiry
Henan Fengda Chemical Co., Ltd +86-371-86557731 +86-13613820652 China 20318 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 57511 58 Inquiry
Henan Anky Chemical Technology Co., Ltd. 17836913271 China 2790 58 Inquiry
Supplier Advantage
CLEARSYNTH LABS LTD. 58
ATK CHEMICAL COMPANY LIMITED 60
career henan chemical co 58
Baoji Guokang Healthchem co.,ltd 58
Guangzhou TongYi biochemistry technology Co.,LTD 58
InvivoChem 58
TargetMol Chemicals Inc. 58
Henan Fengda Chemical Co., Ltd 58
Aladdin Scientific 58
Henan Anky Chemical Technology Co., Ltd. 58
Delpazolid Delpazolid (LCB01-0371) LCB01-0371 CS-2617 DELPAZOLID; LCB01-0371; LCB 01-0371; LCB-01-0371; LCB010371; LCB 010371; LCB-010371 (5R)-3-[4-(5,6-Dihydro-1-methyl-1,2,4-triazin-4(1H)-yl)-3-fluorophenyl]-5-(hydroxymethyl)-2-oxazolidinone Delpazolid/(5R)-3-[4-(5,6-Dihydro-1-methyl-1,2,4-triazin-4(1H)-yl)-3-fluorophenyl]-5-(hydroxymethyl)-2-oxazolidinone 2-Oxazolidinone, 3-[4-(5,6-dihydro-1-methyl-1,2,4-triazin-4(1H)-yl)-3-fluorophenyl]-5-(hydroxymethyl)-, (5R)- (R)-3-(3-fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4(1H)-yl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one (5R)-3-[3-fluoro-4-(1-methyl-1,4,5,6-tetrahydro-1,2, 4-triazin-4-yl)phenyl]-5-(hydroxymethyl)-1,3-oxazo lidin-2-one Antibiotic,Delpazolid,inhibit,Bacterial,Inhibitor 1219707-39-7 C14H17FN4O3