ANTI HUMAN TR-ALPHA
- CAS No.
- Chemical Name:
- ANTI HUMAN TR-ALPHA
- Synonyms
- GRTH;THB1;THR1;EAR7;ERBA2;THRB1;NR1A2;EAR-7;ERBA1;NR1A1
- CBNumber:
- CB3416653
- Molecular Formula:
- Molecular Weight:
- 0
- MOL File:
- Mol file
- Modify Date:
- 2023/4/23 13:52:06
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319 |
| Precautionary statements | P305+P351+P338 |
ANTI HUMAN TR-ALPHA price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | SAB2501036 | Anti-THRA antibody produced in goat affinity isolated antibody, buffered aqueous solution | 100μG | ₹53135.7 | 2022-06-14 | Buy | |
| Sigma-Aldrich(India) | HPA009654 | Anti-THRA antibody produced in rabbit Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution | 100μL | ₹41436.3 | 2022-06-14 | Buy |
ANTI HUMAN TR-ALPHA Chemical Properties,Uses,Production
Uses
Anti-THRA antibody produced in rabbit, a Prestige Antibody, is developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org). Each antibody is tested by immunohistochemistry against hundreds of normal and disease tissues. These images can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. The antibodies are also tested using immunofluorescence and western blotting. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit .
General Description
THRA (thyroid hormone receptor α) belongs to a family of nuclear receptors, which function as ligand-regulated transcription factors and are called thyroid hormone receptors (TRs). THRA is a predominant mammalian TR isoform. This receptor is highly expressed in central nervous system, myocardium, gastrointestinal tract and skeletal muscle.
Biochem/physiol Actions
Conserved lysine in the DNA-binding domain of this receptor functions as a sensor of transcriptional regulation. This lysine is mutated in hepatocellular carcinoma (HCC). Mutations in this protein result in resistance to thyroid hormone, which is alleviated by thyroxine treatment. Population with rs939348 TT polymorphism in this gene show weak relation to increased risk to Alzheimer′s disease. This receptor is also up-regulated in patients with breast cancer.
ANTI HUMAN TR-ALPHA Preparation Products And Raw materials
Raw materials
Preparation Products
ANTI HUMAN TR-ALPHA Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Peptide Institute, Inc. | +81 (0) 72 729 4121 | Japan | 992 | 70 | Inquiry |
| ABR-Affinity BioReagents | 303 278 4535 | United States | 489 | 73 | Inquiry |
| Riedel-de Haen AG | 800 558-9160 | United States | 6825 | 87 | Inquiry |
| Shanghai Huzhen Industrial Co., LTD | 021-60345367 13916550749 | China | 9966 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| Peptide Institute, Inc. | 70 |
| ABR-Affinity BioReagents | 73 |
| Riedel-de Haen AG | 87 |
| Shanghai Huzhen Industrial Co., LTD | 58 |