BETA-ENDORPHIN HUMAN SYNTHETIC

BETA-ENDORPHIN  HUMAN  SYNTHETIC Structure
CAS No.
61214-51-5
Chemical Name:
BETA-ENDORPHIN HUMAN SYNTHETIC
Synonyms
LPH(61-91);βh-Endorphin;B-ENDORPHIN HUMAN;β-Endorphin human;Β-ENDORPHIN, HUMAN;β- endorphin, people;β-Lipotropin C-fragment;β-Endorphin(1-31)【human】;61-91-β-Lipotropin【human】;Human beta-lipotropin(61-91)
CBNumber:
CB3497654
Molecular Formula:
C158H251N39O46S
Molecular Weight:
3464.99
MOL File:
61214-51-5.mol
MSDS File:
SDS
Modify Date:
2024/8/28 13:53:23

BETA-ENDORPHIN HUMAN SYNTHETIC Properties

Boiling point 2931.7±65.0 °C(Predicted)
Density 1.302±0.06 g/cm3(Predicted)
storage temp. −20°C
solubility Soluble in DMSO
form Powder
color White to off-white
optical activity -7420 (0.5 mol dm-3 acetic acid)
Water Solubility Soluble in water.

SAFETY

Risk and Safety Statements

Safety Statements  22-24/25
WGK Germany  3
10

BETA-ENDORPHIN HUMAN SYNTHETIC price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) E6261 β-Endorphin human ≥95% (HPLC) 61214-51-5 250μG ₹15274.08 2022-06-14 Buy
Sigma-Aldrich(India) E6261 β-Endorphin human ≥95% (HPLC) 61214-51-5 0.5MG ₹25720.2 2022-06-14 Buy
Sigma-Aldrich(India) E6261 β-Endorphin human ≥95% (HPLC) 61214-51-5 1MG ₹42845.35 2022-06-14 Buy
Product number Packaging Price Buy
E6261 250μG ₹15274.08 Buy
E6261 0.5MG ₹25720.2 Buy
E6261 1MG ₹42845.35 Buy

BETA-ENDORPHIN HUMAN SYNTHETIC Chemical Properties,Uses,Production

Uses

beta-endorphins produce analgesia by binding to opioid receptors (particularly of the mu subtype) at both pre- and post- synaptic nerve terminals, primarily exerting their effect through presynaptic binding. In the central nervous system, beta-endorphins similarly bind mu-opioid receptors and exert their primary action at presynaptic nerve terminals. It is a potent pain suppressant.

General Description

β-Endorphin is a potent endogenous opioid protein that is derived from propiomelanocortin, a protein found in the brain, anterior pituitary, skin, immune system, and other peripheral sites. β-endorphin, however, is localized to the brain and spinal cord. It is one of the major opioid peptides, and is the derivative of the C-terminal of β-lipotropin. It is made of 31 amino acids.

Biochem/physiol Actions

β-Endorphin acts as a ligand for both μ and δ opioid receptors in different parts of the brain. It is released in response to painful stimuli and has potent antinociceptive activity. When given supraspinally, this activity is mediated through its action on ε-opioid receptors in brain that results in the release of Met-enkephalin. This activity is also mediated by its interaction with δ2-opioid receptors in the spinal cord. When introduced intrathecally, this function is an outcome of its interaction with μ and κ-opioid receptors in the rat. In autoimmune disorders, the elevated production of cytokines results in the production of β-endorphin, in pituitary and lymphocytes. This acts as a negative regulator of antibody production, and is thus, implicated in autoimmune diseases.

BETA-ENDORPHIN HUMAN SYNTHETIC Preparation Products And Raw materials

Raw materials

Preparation Products

BETA-ENDORPHIN HUMAN SYNTHETIC Suppliers

Global( 81)Suppliers
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Xiamen Wonderful Bio Technology Co., Ltd. +8613043004613 China 305 58 Inquiry
Cellmano Biotech Limited 0551-65326643 18156095617 China 999 58 Inquiry
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Hebei Miaoyin Technology Co.,Ltd +86-17367732028 +86-17367732028 China 3581 58 Inquiry
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Sichuan Jisheng Biopharmaceutical +86-0833-2598903 +8619981963231 China 175 58 Inquiry
β-Endorphin, human, ≥96% (HPLC) Β-ENDORPHIN, HUMAN BETA-ENDORPHIN HUMAN SYNTHETIC BETA-ENDORPHIN, HUMAN, SYNTETIC B-ENDORPHIN HUMAN β-Lipotropin 61-91, β-Lipotropin C-fragment, LPH (61-91) 61-91-β-Lipotropin【human】 β-Endorphin(1-31)【human】 βh-Endorphin β-Lipotropin C-fragment TYR-GLY-GLY-PHE-MET-THR-SER-GLU-LYS-SER-GLN-THR-PRO-LEU-VAL-THR-LEU-PHE-LYS-ASN-ALA-ILE-ILE-LYS-ASN-ALA-TYR: YGGFMTSEKSQTPLVTLFKNAIIKNAY 27-L-Tyrosine-31-L-glutamic acid-beta-endorphin (sheep) beta-Endorphin (sheep), 27-L-tyrosine-31-L-glutamic acid- LPH(61-91) β-Endorphin (huMan) β-Lipotropin (59-89) (huMan), Lipotropin C FragMent (huMan) b-Lipotropin (59-89) (huMan), Lipotropin C FragMent (huMan) β- endorphin, people Human beta-lipotropin(61-91) L-Tyrosylglycylglycyl-L-phenylalanyl-L-methionyl-L-threonyl-L-seryl-L-alpha-glutamyl-L-lysyl-L-seryl-L-glutaminyl-L-threonyl-L-prolyl-L-leucyl-L-valyl-L-threonyl-L-leucyl-L-phenylalanyl-L-lysyl-L-asparaginyl-L-alanyl-L-isoleucyl-L-isoleucyl-L-lysyl-L-asparaginyl-L-alanyl-L-tyrosyl-L-lysyl-L-lysylglycyl-L-glutamic acid β-Endorphin (sheep), 27-L-tyrosine-31-L-glutamic acid- β-Endorphin human β-Endorphin (huMan) β-Lipotropin (59-89) (huMan), Lipotropin C FragMent (huMan) 27-L-Tyrosine-31-L-glutamic acid-beta-endorphin β-Endorphin (sheep), 27-L-tyrosine-31-L-glutamic acid- 61214-51-5 C158H251N39O46S