POLYPHYLLIN D
- CAS No.
- 50773-41-6
- Chemical Name:
- POLYPHYLLIN D
- Synonyms
- Paris I;Saponin Pa;Polyphyllin;Polyphyllin C;Polyphyllin I;POLYPHYLLIN D;Polyphyllin A;Polyphillin D;Polyphyllin Ⅰ;GLYCO-DIOSGENIN
- CBNumber:
- CB3511798
- Molecular Formula:
- C44H70O16
- Molecular Weight:
- 855.02
- MOL File:
- 50773-41-6.mol
- Modify Date:
- 2024/6/27 18:15:55
POLYPHYLLIN D Chemical Properties,Uses,Production
Description
Polyphyllin I is a steroid saponin that has been found in P. polyphylla and has anticancer activity. It decreases proliferation of, and induces apoptosis in, MCF-7 and MDA-MB-231 cells (IC50s = 5 and 2.5 μM, respectively). It disrupts the mitochondrial membrane potential, activates caspase-3, and increases protein levels of the caspase-3 substrate poly(ADP-ribose) polymerase (PARP) in HepG2 and drug-resistant R-HepG2 cells. Polyphyllin I (2.05 and 2.73 mg/kg for 10 days) reduces tumor growth in an MCF-7 mouse xenograft model.
Uses
Polyphylin II is a natural saponin extracted from the plant, Paris polyphylla, and displays antiproliferative activity in vivo. Used in the treatment of lung and cervical cancers.
POLYPHYLLIN D Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 176)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Shaanxi Haibo Biotechnology Co., Ltd | +undefined18602966907 | China | 1000 | 58 | Inquiry |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | China | 21668 | 55 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29894 | 58 | Inquiry |
| Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | CHINA | 1824 | 58 | Inquiry |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | China | 3777 | 58 | Inquiry |
| BOC Sciences | +1-631-485-4226 | United States | 19553 | 58 | Inquiry |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | China | 39916 | 58 | Inquiry |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-519-519-85557386 | China | 11006 | 58 | Inquiry |
| Hubei Ipure Biology Co., Ltd | +8613367258412 | China | 10326 | 58 | Inquiry |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | China | 34571 | 58 | Inquiry |
50773-41-6(POLYPHYLLIN D)Related Search:
(25R)-3β-(2-O-α-L-Rhamnopyranosyl-β-D-glucopyranosyloxy)spirosta-5-ene
Nystatin
Mesaconitine
PolyphyllinH
Spiro[8H-naphth[2',1':4,5]indeno[2,1-b]furan-8,2'-[2H]pyran] alpha-D-glucopyranoside deriv.
ANTI-GALECTIN-7
POLYPHYLLIN E (RG)
(3beta,25R)-14-Hydroxyspirost-5-en-3-yl O-6-deoxy-alpha-L-mannopyranosyl-(1-2)-O-[beta-D-xylopyranosyl-(1-4)]-beta-D-glucopyranoside
poricoic acid A 3-methyl ester
Resibufogenin
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POLYPHYLLIN D
Polyphyllin
Polyphyllin I
Polyphyllin C
Paris saponin Pa
Polyphillin D
Polyphyllin A
Paridis saponin I
Paris I
Saponin Pa
Chonglou Saponin I(Polyphyllin A)
Polyphyllin Ⅰ
I,Chonglousaponin
Polyphyllin I(Chonglou Saponin I)
Polyphyllin D / Diosgenyl 4-O-α-L-arabinofuranosyl-2-O-α-L-rhamnopyranosyl-β -D-glucopyranoside
Polyphyllin I, 98%, from Paris polyphylla Smith var.chinensis
GLYCO-DIOSGENIN
β-D-Glucopyranoside, (3β,25R)-spirost-5-en-3-yl O-α-L-arabinofuranosyl-(1→4)-O-[6-deoxy-α-L-mannopyranosyl-(1→2)]-
POLYPHYLLIN D USP/EP/BP
Chondroitin Saponin
50773-41-6
chemical reagent
pharmaceutical intermediate
phytochemical
reference standards from Chinese medicinal herbs (TCM).
standardized herbal extract