TISSUE PLASMINOGEN ACTIVATOR, HUMAN

TISSUE PLASMINOGEN ACTIVATOR, HUMAN Structure
CAS No.
189263-81-8
Chemical Name:
TISSUE PLASMINOGEN ACTIVATOR, HUMAN
Synonyms
TISSUE PLASMINOGEN ACTIVATOR;TPA;TPA, HUMAN;1-CHAIN TPA;2-CHAIN TPA;TISSUE PLASMINOGEN ACTIVATOR, HUMAN;TISSUE PLASMINOGEN ACTIVATOR 2-CHAIN;TISSUE PLASMINOGEN ACTIVATOR 1-CHAIN;9,10-Bis[N-(m-tolyl)anilino]anthracene;9,10-Bis[N-(m-tolyl)anilino]anthracene
CBNumber:
CB3746518
Molecular Formula:
C40H32N2
Molecular Weight:
540.7
MOL File:
189263-81-8.mol
MSDS File:
SDS
Modify Date:
2023/6/8 17:06:34

TISSUE PLASMINOGEN ACTIVATOR, HUMAN Properties

Melting point 262 °C
Boiling point 723.8±53.0 °C(Predicted)
Density 1.194±0.06 g/cm3(Predicted)
storage temp. 2-8°C
pka -0.33±0.50(Predicted)
form Lyophilized
color Light yellow to Yellow to Orange

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Hazard Codes  Xn
Risk Statements  22-36/37/38
Safety Statements  26-36
WGK Germany  1
HS Code  2921.59.8090

TISSUE PLASMINOGEN ACTIVATOR, HUMAN price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) T0831 Tissue plasminogen activator human 189263-81-8 100μG ₹40381.8 2022-06-14 Buy
Sigma-Aldrich(India) T0831 Tissue plasminogen activator human 189263-81-8 1MG ₹105649.8 2022-06-14 Buy
TCI Chemicals (India) B4965 9,10-Bis[N-(m-tolyl)anilino]anthracene 189263-81-8 200MG ₹4100 2022-05-26 Buy
TCI Chemicals (India) B4965 9,10-Bis[N-(m-tolyl)anilino]anthracene 189263-81-8 1G ₹9200 2022-05-26 Buy
Product number Packaging Price Buy
T0831 100μG ₹40381.8 Buy
T0831 1MG ₹105649.8 Buy
B4965 200MG ₹4100 Buy
B4965 1G ₹9200 Buy

TISSUE PLASMINOGEN ACTIVATOR, HUMAN Chemical Properties,Uses,Production

Chemical Properties

off-white powder

Uses

Tissue plasminogen activator has been used in a study to assess treatment risks of intracranial hemorrhage among patients with acute ischemic stroke. Tissue plasminogen activator has also been used in a study to investigate the successful treatment of early thrombosis of HeartWare left ventricular assist devices with intraventricular thrombolytics. Human tissue plasminogen activator has been used to study the effect of tyrosinase-related protein 2 (TRP-2) expression on melanin production in sheep.

General Description

Recombinant tPA (rtPA), alteplase (Activase), is identicalwith endogenous tPA. rtPA lacks a glycosyl residue atAsn184. At one time, rtPA was produced in two-chain formin CHO cultures. Now, large-scale cultures of recombinanthuman melanoma cells in fermenters are used to produce aproduct that is about 80% single-chain rtPA.
Alteplase is used to improve ventricular function followingan acute myocardial infarction, including reducing the incidenceof congestive heart failure and decreasing mortality.The drug is also used to treat acute ischemic stroke aftercomputed tomography (CT) or other diagnostic imaging hasruled out intracranial hemorrhage. rtPA is also used in casesof acute pulmonary thromboembolism and is being investigatedfor unstable angina pectoris.
Alteplase is supplied as powder for injection, and in reconstitutedform (normal saline or 5% dextrose in water) isintended for IV infusion only. The solution expires in 8 hoursat room temperature and must be prepared just before use.

TISSUE PLASMINOGEN ACTIVATOR, HUMAN Preparation Products And Raw materials

Raw materials

Preparation Products

TISSUE PLASMINOGEN ACTIVATOR, HUMAN Suppliers

Global( 68)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Inventichem +918790275459 Telangana, India 155 58 Inquiry
TCI Chemicals (India) Pvt. Ltd. 1800 425 7889 New Delhi, India 6778 58 Inquiry
Career Henan Chemica Co +86-0371-86658258 +8613203830695 China 30253 58 Inquiry
Alfa Chemistry +1-5166625404 United States 21317 58 Inquiry
Hangzhou MolCore BioPharmatech Co.,Ltd. +86-057181025280; +8617767106207 China 49739 58 Inquiry
LEAPCHEM CO., LTD. +86-852-30606658 China 43348 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 57511 58 Inquiry
Amadis Chemical Company Limited 571-89925085 China 131980 58 Inquiry
Beijing Bi Orange Blue Biotechnology Co., Ltd. 15510022373 CHINA 6827 58 Inquiry
Shanghai Hao Zhun Biological Technology Co., Ltd. 15800340161 CHINA 6846 58 Inquiry
2-CHAIN TPA 1-CHAIN TPA Tissue Plasminogen Activator from human melanoma cells 9,10-Bis[N-(m-tolyl)anilino]anthracene TISSUE PLASMINOGEN ACTIVATOR, HUMANphenyl)-N,N'-diphenyl- TISSUE PLASMINOGEN ACTIVATOR, HUMAN TISSUE PLASMINOGEN ACTIVATOR 1-CHAIN TISSUE PLASMINOGEN ACTIVATOR 2-CHAIN TPA, HUMAN TPA 9,10-Bis[N-(m-tolyl)anilino]anthracene 9-N,10-N-bis(3-methylphenyl)-9-N,10-N-diphenylanthracene-9,10-diamine 9,10-Anthracenediamine, N9,N10-bis(3-methylphenyl)-N9,N10-diphenyl- N,N'-Bis(3-methylphenyl)-N,N'-diphenyl-9,10-anthracenediamine N,N'-Diphenyl-N,N'-di(m-tolyl)-9,10-anthracenediamine N9,N10-Diphenyl-N9,N10-di-m-tolylanthracene-9,10-diamine TISSUE PLASMINOGEN ACTIVATOR 189263-81-8 Serum Related EnzymesEnzymes, Inhibitors, and Substrates Therapeutic EnzymesProteolytic Enzymes and Substrates Tissue Plasminogen Activator Application Index Proteases&Protein Sequencing ProteasesApplication Index Selective Proteolytic Enzymes Serum Proteins and Related Enzymes