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JAK3 INHIBITOR VI

JAK3 INHIBITOR VI Structure
CAS No.
856436-16-3
Chemical Name:
JAK3 INHIBITOR VI
Synonyms
JI6;JAK3 INHIBITOR VI
CBNumber:
CB3787012
Molecular Formula:
C19H17N3O4S
Molecular Weight:
383.42098
MOL File:
856436-16-3.mol
Modify Date:
2023/9/4 15:51:00
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JAK3 INHIBITOR VI Properties

storage temp. +2C to +8C
form Yellow solid

JAK3 INHIBITOR VI price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 420126 JAK3 Inhibitor VI - CAS 856436-16-3 - Calbiochem The JAK3 Inhibitor VI, also referenced under CAS 856436-16-3, controls the biological activity of JAK3. This small molecule/inhibitor is primarily use 856436-16-3 5MG ₹21460 2022-06-14 Buy
Product number Packaging Price Buy
420126 5MG ₹21460 Buy

JAK3 INHIBITOR VI Chemical Properties,Uses,Production

General Description

A cell-permeable, potent, and reversible inhibitor of Janus kinase 3 (JAK3) (IC50 = 27 nM). Reported to bind to the enzyme active site and prevent IL-2-induced phosphorylation of JAK3 and STAT5. Also reported to inhibit IL-2-induced cell proliferation (IC50 = 760 nM for murine CTLL cells and 250 nM for human T-cells). Shown to alleviate oxazolone-induced ear edema in mice with an efficacy comparable to Dexamethasone (Cat. No. 265005) and displays ~16-fold greater selectivity over JAK2.

Biochem/physiol Actions

Cell permeable: yes

JAK3 INHIBITOR VI Preparation Products And Raw materials

Raw materials

Preparation Products

JAK3 INHIBITOR VI Suppliers

Global( 9)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
EMD Biosciences, Inc. 858 450 5500 United States 6529 66 Inquiry
Beijing Anbiqi Biotechnology Co., Ltd. 15811277462 CHINA 2529 58 Inquiry
Beijing Baiao Innovation Technology Co., Ltd. 010-5718533 13366620421 CHINA 6005 58 Inquiry
Beijing Fubo Biotechnology Co., Ltd. 010-57263844 13260236521 CHINA 6039 58 Inquiry
Creative Enzymes 1-516-855-7709 United States 6057 58 Inquiry
Tianjin Kailiqi Biotechnology Co., Ltd. 15076683720 China 3717 55 Inquiry
Beijing Biocreative Technology Co., Ltd. 15522676233 China 1249 58 Inquiry
Sigma-Aldrich 021-61415566 800-8193336 China 51471 80 Inquiry
TargetMol Chemicals Inc. 15002134094 China 28118 58 Inquiry
Supplier Advantage
EMD Biosciences, Inc. 66
Beijing Anbiqi Biotechnology Co., Ltd. 58
Beijing Baiao Innovation Technology Co., Ltd. 58
Beijing Fubo Biotechnology Co., Ltd. 58
Creative Enzymes 58
Tianjin Kailiqi Biotechnology Co., Ltd. 55
Beijing Biocreative Technology Co., Ltd. 58
Sigma-Aldrich 80
TargetMol Chemicals Inc. 58

JAK3 INHIBITOR VI Spectrum

JAK3 INHIBITOR VI(856436-16-3)1HNMR
JAK3 INHIBITOR VI JI6 856436-16-3