ChemicalBook > Product Catalog >Biochemical Engineering >Polypeptide >SUBSTANCE P

SUBSTANCE P

CAS No.: 33507-63-0

Chemical Name:: SUBSTANCE P

Synonyms: Sub;TYR8;RPKPQFFGLM;Aids114081;SUBSTANCE P;P substance;Aids-114081;Neurokinin P;RPKPQQFFGLM-NH2;substance P (SP)

CBNumber:: CB4114260

Molecular Formula:: C63H98N18O13S

Molecular Weight:: 1347.63

MOL File:: 33507-63-0.mol

Modify Date:: 2024/4/19 20:05:26

Request For Quotation

SUBSTANCE P Properties

Melting point	148 °C
Density	1.42±0.1 g/cm3(Predicted)
storage temp.	−20°C
solubility	H₂O: 1 mg/mL
pka	13.26±0.46(Predicted)
form	powder
color	white
Water Solubility	Soluble in water, DMSO, and Acetic Acid.
Sequence	H-Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2
InChIKey	ADNPLDHMAVUMIW-UHFFFAOYSA-N

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H312-H332-H302
Precautionary statements	P280-P302+P352-P312-P322-P363-P501-P261-P271-P304+P340-P312-P264-P270-P301+P312-P330-P501
WGK Germany	3
F	3-10-21

SUBSTANCE P price More Price(3)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	05-23-0600	Substance P - CAS 33507-63-0 - Calbiochem Neuropeptide found in high concentrations in the gut.	33507-63-0	1MG	₹5810	2022-06-14	Buy
Sigma-Aldrich(India)	05-23-0600	Substance P - CAS 33507-63-0 - Calbiochem Neuropeptide found in high concentrations in the gut.	33507-63-0	5MG	₹18830	2022-06-14	Buy
Sigma-Aldrich(India)	05-23-0600	Substance P - CAS 33507-63-0 - Calbiochem Neuropeptide found in high concentrations in the gut.	33507-63-0	25MG	₹41350	2022-06-14	Buy

Product number	Packaging	Price	Buy
05-23-0600	1MG	₹5810	Buy
05-23-0600	5MG	₹18830	Buy
05-23-0600	25MG	₹41350	Buy

SUBSTANCE P Chemical Properties,Uses,Production

Uses

Substance P is a neurokinin undecapeptide neurotransmitter and neuromodulator.

General Description

Substance P is a polypeptide consisting of 11 amino acidresidues. It has been implicated in the transmission of“painful” sensory information through the spinal cord tohigher centers in the central nervous system. Substance Pis localized in the primary afferent sensory fibers. Other pharmacologicaleffects are vasodilatation, stimulation of smoothmuscles, stimulation of salivary secretion, and diuresis. In addition,this neuropeptide contributes to some inflammatory responses.Approximately 50% of the known neuropeptides aresynthesized as biologically inactive glycine extended precursorsthat require a carboxy-terminal posttranslational amidationfor biological activity. Amidation enzymes are responsiblefor the conversion of the carboxyl group of the neuropeptide tothe corresponding amide group and include the two amidatingenzymes peptidylglycine α-monooxygenase (PAM) and peptidylamidoglycolatelyase (PGL), which work sequentially toproduce the inflammatory neuropeptide Substance P from aninactive precursor peptide. Much research is being performedto exploit this mechanism of inflammation.

SUBSTANCE P Preparation Products And Raw materials

Raw materials

Electrophoresis

Preparation Products

SUBSTANCE P Suppliers

Global( 179)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
BOC Sciences	16314854226; +16314854226	United States	19743	58	Inquiry
Shanghai Getian Industrial Co., LTD	+86-15373193816 +86-15373193816	China	269	58	Inquiry
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	China	16209	58	Inquiry
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	China	10318	58	Inquiry
Chongqing Chemdad Co., Ltd	+86-023-6139-8061 +86-86-13650506873	China	39916	58	Inquiry
Cellmano Biotech Limited	0551-65326643 18156095617	China	999	58	Inquiry
career henan chemical co	+86-0371-86658258 +8613203830695	China	29826	58	Inquiry
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	China	25247	58	Inquiry
Baoji Guokang Healthchem co.,ltd	+8615604608665 15604608665	CHINA	9427	58	Inquiry
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	China	10522	58	Inquiry

Supplier	Advantage
BOC Sciences	58
Shanghai Getian Industrial Co., LTD	58
Shanghai Daken Advanced Materials Co.,Ltd	58
Shenzhen Nexconn Pharmatechs Ltd	58
Chongqing Chemdad Co., Ltd	58
Cellmano Biotech Limited	58
career henan chemical co	58
Dideu Industries Group Limited	58
Baoji Guokang Healthchem co.,ltd	58
Zhejiang J&C Biological Technology Co.,Limited	58

SUBSTANCE P Spectrum

SUBSTANCE P(33507-63-0)MS

33507-63-0(SUBSTANCE P)Related Search:

SUBSTANCE P LYS-PRO-GLN-GLN-PHE-PHE-GLY-LEU-MET-NH2 ARG-PRO-LYS-PRO-GLN-GLN-PHE-PHE-GLY-LEU-MET-NH2 3ACOH 5H2O GLY-LEU-MET-NH2 SUBSTANCE P (1-7)

SUBSTANCE P (2-11) SUBSTANCE P (1-9) ARG-PRO-LYS-PRO-GLN-GLN-PHE-PHE-GLY-LEU-MET-OME SUBSTANCE P (5-11) SUBSTANCE P (7-11)

SUBSTANCE P (4-11) SUBSTANCE P (1-4) PANCREATIC POLYPEPTIDE, RAT SUBSTANCE P (6-11) Substance P (1-7)(TFA)

NEUROPEPTIDE Y (13-36), PORCINE SYNTHETI C >97% substance P (3-11) (LEU31,PRO34)-NEUROPEPTIDE Y (HUMAN, RAT)

chevron_left

1of4

chevron_right

ARG-PRO-LYS-PRO-GLN-GLN-PHE-PHE-GLY-LEU-MET-NH2 H2N-ARG-PRO-LYS-PRO-GLN-GLN-PHE-PHE-GLY-LEU-MET H-ARG-PRO-LYS-PRO-GLN-GLN-PHE-PHE-GLY-LEU-MET-NH2 SUBSTANCE P, F & D VERSION OF S6883*ACET ATE (2S)-2-[[(2S)-1-[(2S)-6-amino-2-[[(2S)-1-[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-N-[(2S)-5-amino-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1,5-dioxopentan-2-yl]pentanediamide SUBSTANCE P (HUMAN, BOVINE, RAT, MOUSE) SUBSTANCE P BOVINE SUBSTANCE P, [D-ARG1, D-PRO2, D-TRP7,9, LEU11] SUBSTANCE P (TYR8) SUBSTANCE P SUBSTANCE P AMIDE RPKPQFFGLM RPKPQQFFGLM-NH2 substance P (SP) L-Arg-L-Pro-L-Lys-L-Pro-L-Gln-L-Gln-L-Phe-L-Phe-Gly-L-Leu-L-Met-NH2 L-Arg-L-Pro-L-Lys-L-Pro-L-Gln-L-Gln-L-Phe-L-Phe-Gly-L-Leu-Met-NH2 L-Arg-L-Pro-L-Lys-L-Pro-L-Glu(NH2)-L-Glu(NH2)-L-Phe-L-Phe-Gly-L-Leu-L-Met-NH2 Neurokinin P P substance Sub Aids114081 Aids-114081 (S)-N1-((5S,8S,14S,17S,20S)-23-aMino-14,17-dibenzyl-5-carbaMoyl-8-isobutyl-7,10,13,16,19,23-hexaoxo-2-thia-6,9,12,15,18-pentaazatricosan-20-yl)-2-((S)-1-((S)-6-aMino-2-((S)-1-((S)-2-aMino-5-guanidinopentanoyl)pyrrolidine-2-carboxaMido)hexanoyl)pyrrolidine H-Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2 acetate salt Substance P TFA salt Substance P Acetate Substance P,Neurokinin P,Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2,RPKPQQFFGLM-NH2?, >98% TYR8 SUBSTANCE P USP/EP/BP Substance P，Neurokinin P，Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2，RPKPQQFFGLM-NH2 Substance P (9CI, ACI) NK receptor,Neurokinin Receptor,Endogenous Metabolite,Substance P,inhibit,Tachykinin receptor,Inhibitor 33507-63-0free/12769-48-1 P substance amide, Neurokinin P Amide sh-Oligopeptide-73 33507-63-0 C63H98N18O13S C63H98N18O13S1 Tachykinins Peptides Biochemicals and Reagents BioChemical Agonist Amino Acids and Peptides Peptide Tachykinin receptor TPI Peptide Receptors