Bulaquine
- CAS No.
- 79781-00-3
- Chemical Name:
- Bulaquine
- Synonyms
- Bulaquine;CDRI-80/53;aablaquine;compound 80-53;N-[(3-Acetyl-4,5-dihydrofuran)-2-yl]-N'-(6-methoxy-8-quinolinyl)-1,4-pentanediamine;1-[4,5-Dihydro-2-[[4-[(6-methoxyquinoline-8-yl)amino]pentyl]amino]furan-3-yl]ethanone;2(3H)-Furanone, dihydro-3-[1-[[4-[(6-methoxy-8-quinolinyl)amino]pentyl]amino]ethylidene]-
- CBNumber:
- CB41344929
- Molecular Formula:
- C21H27N3O3
- Molecular Weight:
- 369.46
- MOL File:
- 79781-00-3.mol
- Modify Date:
- 2023/5/4 17:34:42
Bulaquine Chemical Properties,Uses,Production
Description
Bulaquine is a derivative of primaquine that was introduced in India in combination with chloroquine as a treatment against malaria. The compound is prepared by condensation of primaquine with 3-acetyl-y-butyrolactone in presence of a catalytic amount of base. Bulaquine kills the latent tissue stage (hypnozoites) of the parasite Plasmodium vivax accumulated in the liver and responsible for relapses. Its efficient anti-relapse activity was demonstrated against sporozoite induced Plasmodium cynomolgi infection in rhesus monkey. Bulaquine is safer than primaquine, the preceding candidate against malaria relapse. Although it is stable at pH 7-8, bulaquine is hydrolyzed to primaquine under acidic conditions.
Originator
CDRI (India)
brand name
Aablaquin
Bulaquine Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 5)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Clearsynth Labs Research Centre | 08048372785Ext 201 | Mallapur, India | 9 | 58 | Inquiry |
| TargetMol Chemicals Inc. | +1-781-999-5354 | United States | 19973 | 58 | Inquiry |
| Chengdu Push Bio-Technology Co., Ltd. | 18080489829 | China | 9209 | 58 | Inquiry |
| TargetMol Chemicals Inc. | 4008200310 | China | 23980 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| CLEARSYNTH LABS LTD. | 58 |
| Clearsynth Labs Research Centre | 58 |
| TargetMol Chemicals Inc. | 58 |
| Chengdu Push Bio-Technology Co., Ltd. | 58 |
| TargetMol Chemicals Inc. | 58 |
79781-00-3(Bulaquine)Related Search:
compound 80-53
1-[4,5-Dihydro-2-[[4-[(6-methoxyquinoline-8-yl)amino]pentyl]amino]furan-3-yl]ethanone
CDRI-80/53
N-[(3-Acetyl-4,5-dihydrofuran)-2-yl]-N'-(6-methoxy-8-quinolinyl)-1,4-pentanediamine
Bulaquine
2(3H)-Furanone, dihydro-3-[1-[[4-[(6-methoxy-8-quinolinyl)amino]pentyl]amino]ethylidene]-
aablaquine
79781-00-3