4-HYDROXY-3-(HYDROXYMETHYL)BENZALDEHYDE

4-HYDROXY-3-(HYDROXYMETHYL)BENZALDEHYDE Structure
CAS No.
54030-32-9
Chemical Name:
4-HYDROXY-3-(HYDROXYMETHYL)BENZALDEHYDE
Synonyms
Salbutamol EP Impurity Q;Salbutamol EP Impurity 14;Salbutamol Related Compound 3;4-HYDROXY-3-(HYDROXYMETHYL)BENZALDEHYDE;Benzaldehyde, 4-hydroxy-3-(hydroxymethyl)-;4-Hydroxy-3-(hydroxymethyl)benzaldehyde, tech.;Salbutamol Impurity 18(Salbutamol EP Impurity Q)
CBNumber:
CB41507300
Molecular Formula:
C8H8O3
Molecular Weight:
152.15
MOL File:
54030-32-9.mol
MSDS File:
SDS
Modify Date:
2022/12/21 16:56:50

4-HYDROXY-3-(HYDROXYMETHYL)BENZALDEHYDE Properties

Melting point 142-145 °C
Boiling point 342.6±32.0 °C(Predicted)
Density 1.342±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
pka 7.74±0.18(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338

4-HYDROXY-3-(HYDROXYMETHYL)BENZALDEHYDE Chemical Properties,Uses,Production

Uses

4-Hydroxy-3-(hydroxymethyl)benzaldehyde is an impurity of Albuterol (A514501) which is a β2-adrenoceptor agonist, a bronchodilator and a tocolytic. 4-Hydroxy-3-(hydroxymethyl)benzaldehyde is also used in the preparation of Cinnamyl alcohol-like compounds which can be used for treatment of free radical generated related diseases inlcuding auto-immunodeficiency diseases. It is also used as a reagent in the synthesis of 5-Diacetoxymethyl-cycloSal-d4TMP which is a prototype of enzymatically activated cycloSal-pronucleotides that may possess antiviral activities against HIV.

4-HYDROXY-3-(HYDROXYMETHYL)BENZALDEHYDE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-HYDROXY-3-(HYDROXYMETHYL)BENZALDEHYDE 4-Hydroxy-3-(hydroxymethyl)benzaldehyde, tech. Salbutamol Related Compound 3 Benzaldehyde, 4-hydroxy-3-(hydroxymethyl)- Salbutamol Impurity 18(Salbutamol EP Impurity Q) Salbutamol EP Impurity Q Salbutamol EP Impurity 14 54030-32-9