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cis-Octahydro-1H-isoindole hydrochloride

 cis-Octahydro-1H-isoindole hydrochloride Structure
CAS No.
161829-92-1
Chemical Name:
cis-Octahydro-1H-isoindole hydrochloride
Synonyms
Cis-hexahydroisoindolineHCL;Cis-hexahydroisoindole, HCl;cis-Octahydroisoindole hydrochloride;Cis-Hexahydroisoindoline hydrochloride;CIS-HEXAHYDROISOINDOLINE HYDROGEN CHLORIDE;(3aR,7aS)-octahydro-1H-isoindole hydrochloride;(3aR,7aS)-rel-Octahydro-1H-isoindole hydrochloride;rel-(3aR,7aS)-Octahydro-1H-isoindole hydrochloride;(3aR,7aS)-octahydro-1H-isoindole hydrochloride (1:1);(3aR,7aS)-rel-octahydro-1H-Isoindole, hydrochloride (1:1)
CBNumber:
CB42130400
Molecular Formula:
C8H16ClN
Molecular Weight:
161.67234
MOL File:
161829-92-1.mol
MSDS File:
SDS
Modify Date:
2023/9/20 11:35:54

cis-Octahydro-1H-isoindole hydrochloride Properties

Melting point 121-123 °C
storage temp. Sealed in dry,Room Temperature
InChI InChI=1/C8H15N.ClH/c1-2-4-8-6-9-5-7(8)3-1;/h7-9H,1-6H2;1H/t7-,8+;
InChIKey CLQIZUYXKFTUEB-KVZVIFLMNA-N
SMILES [H][C@]12CCCC[C@@]1([H])CNC2.Cl |&1:1,6,r|

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P233-P260-P261-P264-P271-P280-P302+P352-P304-P304+P340-P305+P351+P338-P312-P321-P332+P313-P337+P313-P340-P362-P403-P403+P233-P405-P501
HS Code  2933998090

cis-Octahydro-1H-isoindole hydrochloride Chemical Properties,Uses,Production

Description

Cis-Octahydro-1H-isoindole hydrochloride is an important intermediate in the synthesis of mitiglinide which is a new oral hypoglycemic drug for the treatment of type II diabetes for the first marked in Japan

Preparation

Phthalimide was used as raw material to react with KOH. Benzyl bromide was subsequently added to the solution to obtain the N-benzylphthalimide. The addition of lithium tetrahydroaluminum, reducing compound N-benzylphthalimide, yields N-benzyldihydroisoindole. Finally, cis-Octahydro-1H-isoindole hydrochlorid is obtained by Pd/C catalysis and reduction

cis-Octahydro-1H-isoindole hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Hebei Mojin Biotechnology Co., Ltd +86 13288715578 +8613288715578 China 12840 58 Inquiry
CIS-HEXAHYDROISOINDOLINE HYDROGEN CHLORIDE (3aR,7aS)-rel-Octahydro-1H-isoindole hydrochloride (3aR,7aS)-rel-octahydro-1H-Isoindole, hydrochloride (1:1) 1H-Isoindole,octahydro-, hydrochloride, (3aR,7aS)-rel- (9CI) cis-Octahydroisoindole hydrochloride Cis-hexahydroisoindolineHCL 5-[2-(4-{[(1S)-4-ethoxy-1-(ethoxycarbonyl)-4-oxobutyl]carbamoyl}phenyl)ethyl]-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-2-aminium (3aR,7aS)-octahydro-1H-isoindole hydrochloride (3aR,7aS)-2,3,3a,4,5,6,7,7a-Octahydro-1H-isoindole hydrochloride (3aR,7aS)-octahydro-1H-isoindole hydrochloride (1:1) rel-(3aR,7aS)-Octahydro-1H-isoindole hydrochloride Cis-Hexahydroisoindoline hydrochloride Cis-hexahydroisoindole, HCl 161829-92-1