(+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol

(+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol Structure
CAS No.
106083-71-0
Chemical Name:
(+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol
Synonyms
GW 353162;GW-353162A;BW-306U;Bupropion Morpholinol IMpurity;SS-hydroxybupropion hydrochloride;Bupropion Morpholinol (2S,3S)-Isomer;(2S,3S)-Hydroxybupropion hydrochloride;Bupropion Morpholinol IMpurity (HCl Salt);(2S,3S)-Hydroxybupropion hydrochloride >=98% (HPLC);(+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol;(+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol
CBNumber:
CB42502638
Molecular Formula:
C13H19Cl2NO2
Molecular Weight:
292.2
MOL File:
106083-71-0.mol
MSDS File:
SDS
Modify Date:
2023/6/8 9:03:05

(+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol Properties

storage temp. -20°C
solubility DMSO: ≥12mg/mL
form powder
color white to tan

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H319
Precautionary statements  P305+P351+P338
Hazard Codes  Xi
Risk Statements  36
Safety Statements  26
WGK Germany  3
NFPA 704
0
2 0

(+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) H3167 (2S,3S)-Hydroxybupropion hydrochloride ≥98% (HPLC) 106083-71-0 5MG ₹15263.25 2022-06-14 Buy
Sigma-Aldrich(India) H3167 (2S,3S)-Hydroxybupropion hydrochloride ≥98% (HPLC) 106083-71-0 25MG ₹59916.38 2022-06-14 Buy
Product number Packaging Price Buy
H3167 5MG ₹15263.25 Buy
H3167 25MG ₹59916.38 Buy

(+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol Chemical Properties,Uses,Production

Uses

Antidepressant; antianxiety.

General Description

(2S,3S)-hydroxybupropion is a major metabolite of bupropion.

Biochem/physiol Actions

(2S,3S)-hydroxybupropion is a dopamine transporter (DAT) and norepinephrine transporter (NET) transporters inhibitor and nicotinic acetylcholine receptor (nAChR) family modulator. Hydroxybupropions were reported to contribute to antidepressant and perhaps smoking cessation activities. Both (2S,3S) and (2R,3R) metabolites reverse affective and somatic withdrawal signs in nicotine-dependent mice, but (2S,3S)-hydroxybupropion is more potent. (2S,3S)-hydroxybupropion significantly decreases the development of nicotine reward in mice.

(+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 48)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
SynZeal Research Pvt Ltd +1 226-802-2078 Gujarat, India 6522 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
Hangzhou MolCore BioPharmatech Co.,Ltd. +86-057181025280; +8617767106207 China 49739 58 Inquiry
China National Standard Pharmaceutical Corporation Limited +8615391658522 China 11927 58 Inquiry
Amadis Chemical Company Limited 571-89925085 China 131980 58 Inquiry
Shanghai Hao Zhun Biological Technology Co., Ltd. 15800340161 CHINA 6846 58 Inquiry
Guangzhou Dreampharm Biotechnology Co., Ltd. 020-36607679 17825480238 China 9843 12 Inquiry
Energy Chemical 021-58432009 400-005-6266 China 44843 58 Inquiry
Guangzhou Juntang Technology Co., Ltd 020-36607679 13502246435 China 10951 58 Inquiry
(+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethyl-2-morpholinol hydrochloride (2S,3S)-2-(3-Chlorophenyl)-3,5,5-trimethyl-2-morpholinol hydrochloride (2S,3S)-Hydroxybupropion hydrochloride GW 353162 SS-hydroxybupropion hydrochloride (+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol Bupropion Morpholinol IMpurity Bupropion Morpholinol IMpurity (HCl Salt) Bupropion Morpholinol (2S,3S)-Isomer GW-353162A;BW-306U (2S,3S)-Hydroxybupropion hydrochloride >=98% (HPLC) (+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol 106083-71-0