(1R,2S)-2-fluorocyclopropanecarboxylic acid
- CAS No.
- 167073-08-7
- Chemical Name:
- (1R,2S)-2-fluorocyclopropanecarboxylic acid
- Synonyms
- (1R,2S)-2-fluorocyclopropane-1-carboxylic acid;Sitafloxacin Impurity 26;(1R,2S)-2-fluorocyclopropanecarboxylic acid;(1R,2S)-trans-2-Fluorocyclopropanecarboxylic acid 97%;Cyclopropanecarboxylic acid, 2-fluoro-, (1R-trans)- (9CI)
- CBNumber:
- CB42610540
- Molecular Formula:
- C4H5FO2
- Molecular Weight:
- 104.08
- MOL File:
- 167073-08-7.mol
- Modify Date:
- 2024/1/4 9:26:36
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS02 |
|---|---|
| Signal word | Danger |
| Hazard statements | H225 |
| Precautionary statements | P210-P273-P243-P403 |
| HS Code | 2916200090 |
(1R,2S)-2-fluorocyclopropanecarboxylic acid Chemical Properties,Uses,Production
Synthesis
Dissolve benzyl alcohol and allyl bromide in the solvent, add sodium hydride, and perform a condensation reaction to obtain allyl benzyl ether. The obtained allyl benzyl ether, dichlorofluoromethane, and sodium hydroxide solution are raw materials for carbene reaction to obtain 2-chloro-2-fluorocyclopropylmethyl benzyl ether. Subsequently, the obtained 2-chloro-2-fluorocyclopropylmethylbenzyl ether is hydrogenated and reduced to obtain 2-chloro-2-fluorocyclopropanemethanol. Sodium hypochlorite is added as an oxidizing agent to perform an oxidation reaction to obtain 2-chloro-2-fluorocyclopropanecarboxylic acid. Finally, diethylamine is added to perform a hydrogenation reduction reaction to obtain (1R,2S)-2-fluorocyclopropanecarboxylic acid.
(1R,2S)-2-fluorocyclopropanecarboxylic acid Preparation Products And Raw materials
Raw materials
Preparation Products
(1R,2S)-2-fluorocyclopropanecarboxylic acid Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Suzhou Chukai Pharma Tech Co.,Ltd | +8615062531973 | China | 364 | 58 | Inquiry |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | China | 29798 | 60 | Inquiry |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | China | 18642 | 58 | Inquiry |
| Accela ChemBio Inc. | +1-858-6993322 | United States | 19479 | 58 | Inquiry |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | China | 39916 | 58 | Inquiry |
| Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 | China | 10297 | 58 | Inquiry |
| LEAP CHEM CO., LTD. | +86-852-30606658 | China | 24738 | 58 | Inquiry |
| Golden Pharma Co., Limited | +undefined18958062155 | China | 5905 | 58 | Inquiry |
| Henan Aochuang Chemical Co.,Ltd. | +86-0371-63689365 +8618638391208 | China | 9407 | 58 | Inquiry |
| Nantong HI-FUTURE Biology Co., Ltd. | +undefined18051384581 | China | 3136 | 58 | Inquiry |
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