3-Ethoxy-4-Methoxy-alpha-[(Methylsulfonyl)Methyl]-benzeneMethanaMine

3-Ethoxy-4-Methoxy-alpha-[(Methylsulfonyl)Methyl]-benzeneMethanaMine Structure
CAS No.
253168-94-4
Chemical Name:
3-Ethoxy-4-Methoxy-alpha-[(Methylsulfonyl)Methyl]-benzeneMethanaMine
Synonyms
1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethan-1-amine;1-(3-Ethoxy-4-Methoxyphenyl)-2-MethylsulfonylethylaMine;Apr-im B;Apremilast int;RSYY(Avanafil)-36;Apremilast Impurity W;Apremilast Impurity 42;ApreMilast interMediate;Apremilast EP Impurity H;Apremilast Intermediate I
CBNumber:
CB42682646
Molecular Formula:
C12H19NO4S
Molecular Weight:
273.35
MOL File:
253168-94-4.mol
MSDS File:
SDS
Modify Date:
2024/3/19 13:53:49

3-Ethoxy-4-Methoxy-alpha-[(Methylsulfonyl)Methyl]-benzeneMethanaMine Properties

Melting point 120 °C
Boiling point 469.6±45.0 °C(Predicted)
Density 1.195±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility Chloroform (Slightly, Heated, Sonicated), DMSO (Slightly, Heated), Methanol (Slightly)
pka 6.84±0.10(Predicted)
form Solid
color White to Off-White

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501
HS Code  2922.50.4000
NFPA 704
0
2 0

3-Ethoxy-4-Methoxy-alpha-[(Methylsulfonyl)Methyl]-benzeneMethanaMine price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemicals (India) E1381 1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanamine min. 98.0 % 253168-94-4 1G ₹3300 2022-05-26 Buy
TCI Chemicals (India) E1381 1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanamine min. 98.0 % 253168-94-4 5G ₹9800 2022-05-26 Buy
Product number Packaging Price Buy
E1381 1G ₹3300 Buy
E1381 5G ₹9800 Buy

3-Ethoxy-4-Methoxy-alpha-[(Methylsulfonyl)Methyl]-benzeneMethanaMine Chemical Properties,Uses,Production

Uses

1-(3-Ethoxy-4-methoxy-phenyl)-2-methanesulfonylethylamine is used in the enantioselective synthesis of Apremilast (A729700) aminosulfone using catalytic asymetric hydrogenation. Apremilast EP Impurity H

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1-(3-Ethoxy-4-methoxy-phenyl)-2-methanesulfonyl-ethylamine 1.1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethan-1-amine 2-(3-ethoxy-4-methoxyphenyl)-1-(methylsulfonyl)eth-2-ylamine 3-Ethoxy-4-Methoxy-alpha-[(Methylsulfonyl)Methyl]-benzeneMethaMine 3-Ethoxy-4-Methoxy-alpha-[(Methylsulfonyl)Methyl]-benzeneMethanaMine 1-(3-ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethanaMine BenzeneMethanaMine, 3-ethoxy-4-Methoxy-a-[(Methylsulfonyl)Methyl]- ApreMilast interMediate Benzenemethanamine, 3-ethoxy-4-methoxy-α-[(methylsulfonyl)methyl]- Apremilast Intermediate I 3-Ethoxy-4-methoxy-alpha-[(methylsulfonyl)methyl]-benzenemethanamine 1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethylamine Apremilast EP Impurity H (Apremilast Des Acetamidophthalic acid Impurity) Apremilast Impurity W 1-(3-Ethoxy-4-methoxy-phenyl)-2-methanesulfonylethylamine (~10% inorganics) 3-ethoxy-4-methoxy-a-[(methylsulfonyl)methyl]-Benzenemethanamine Apremilast EP Impurity H 1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanamine Apremilast 1-(3-Ethoxy-4-methoxyphenyl)-2- (methylsulofonyl)ethan-1-amine 3-Ethoxy-4-methoxy-α-[(methylsulfonyl)methyl]benzenemethanamine Apremilast Impurity 42 Apremilast int 1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethan-1-amine 1-(3-Ethoxy-4-Methoxyphenyl)-2-MethylsulfonylethylaMine Apr-im B 3- ethoxy -4- methoxy -alpha-[ (methylsulfonyl) methyl]-benzylamine RSYY(Avanafil)-36 3-Ethoxy-4-methoxy-α-[(methylsulfonyl)methyl]benzenemethanamine 1-(3-ethoxy-4-methoxyphenyl)-2-(methyl sulfonyl) ethanamine (EP-imp-H) 3-ethoxy-4-methoxy-ALPHA - [(methylsulfonyl) methyl] - phenylmethylamine 1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanamine (Apremilast Impurity) Amino Sulfone Impurity of Apremilast 253168-94-4 253168-94-5 apremilast intermediates