ChemicalBook > Product Catalog >Organic Chemistry >Alcohols,Phenols,Phenol alcohols >3,4-Dimethoxyphenethylamine

3,4-Dimethoxyphenethylamine

3,4-Dimethoxyphenethylamine Structure
CAS No.
120-20-7
Chemical Name:
3,4-Dimethoxyphenethylamine
Synonyms
HOMOVERATRYLAMINE;2-(3,4-Dimethoxyphenyl)ethanamine;DiMethoxyphenethylaMine;dmpea;Dimethoxyphenylethylamine;2-(3,4-DIMETHOXYPHENYL)ETHYLAMINE;Homoveratrile Amine;3,4-DIMETHOXY PHENYLETHYLAMINE;3,4- twoMethoxy phenylethylaMine;2-(3,4-DiMethoxyphenyl)-1-aMinoethane
CBNumber:
CB4294076
Molecular Formula:
C10H15NO2
Molecular Weight:
181.23
MOL File:
120-20-7.mol
Modify Date:
2024/7/25 20:04:51

3,4-Dimethoxyphenethylamine Properties

Melting point 12-15 °C
Boiling point 188 °C15 mm Hg(lit.)
Density 1.074 g/mL at 25 °C(lit.)
vapor pressure 0.348-0.348Pa at 25℃
refractive index n20/D 1.546(lit.)
Flash point >230 °F
storage temp. Refrigerator
solubility Chloroform (Slightly), Methanol (Slightly)
form Viscous Liquid
pka 9.74±0.10(Predicted)
Specific Gravity 1.10
color Clear light yellow to orange or slightly brownish
PH 11.4 (100g/l, H2O, 20℃)
explosive limit 0.1-1.7%(V)
Water Solubility SOLUBLE
Sensitive Air Sensitive
InChIKey ANOUKFYBOAKOIR-UHFFFAOYSA-N
LogP 0.77
CAS DataBase Reference 120-20-7(CAS DataBase Reference)
NIST Chemistry Reference Benzeneethanamine, 3,4-dimethoxy-(120-20-7)
EPA Substance Registry System Benzeneethanamine, 3,4-dimethoxy- (120-20-7)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS05,GHS07
Signal word  Danger
Hazard statements  H302-H315-H317-H318
Precautionary statements  P261-P264-P280-P301+P312-P302+P352-P305+P351+P338
Hazard Codes  Xn,Xi
Risk Statements  22-36/37/38
Safety Statements  26-36-37/39
RIDADR  UN 2735
WGK Germany  3
RTECS  SH2300000
10
Hazard Note  Irritant
TSCA  Yes
HazardClass  8
PackingGroup  III
HS Code  29222900
Toxicity mouse,LD50,intraperitoneal,181mg/kg (181mg/kg),Yakugaku Zasshi. Journal of Pharmacy. Vol. 97, Pg. 1117, 1977.
NFPA 704
1
2 0

3,4-Dimethoxyphenethylamine price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemicals (India) D0678 Homoveratrylamine min. 98.0 % 120-20-7 25G ₹3400 2022-05-26 Buy
TCI Chemicals (India) D0678 Homoveratrylamine min. 98.0 % 120-20-7 100G ₹8600 2022-05-26 Buy
TCI Chemicals (India) D0678 Homoveratrylamine min. 98.0 % 120-20-7 500G ₹33700 2022-05-26 Buy
ottokemi H 1436 Homoveratrylamine 97% 120-20-7 100gm ₹17910 2022-05-26 Buy
Product number Packaging Price Buy
D0678 25G ₹3400 Buy
D0678 100G ₹8600 Buy
D0678 500G ₹33700 Buy
H 1436 100gm ₹17910 Buy

3,4-Dimethoxyphenethylamine Chemical Properties,Uses,Production

Description

3,4-Dimethoxyphenylethylamine, also known as 3,4-DMPEA or DMPEA is an endogenous metabolite found in urine that belongs to both the phenethylamine and catecholamine families. DMPEA is an analogue of dopamine (3,4-dihydroxyphenethylamine), with a substitution of the hydroxy groups with methoxy groups. It is also structurally similar to mescaline (3,4,5-trimethoxyphenylethylamine) and occurs naturally alongside it in various species of cacti such as the San Pedro and Peruvian Torch. DMPEA received wide attention after it was proposed as a biomarker in schizophrenic patients urine, however later studies revealed that DMPEA is also excreted by non-schizophrenics. DMPEA has little known bioactivity, but it has some action as a monoamine oxidase inhibitor. It has also been shown to have neurotoxic effects, especially in the nigrostriatal system and among dopaminergic neurons. DMPEA appears to be an inhibitor of mitochondrial complex I.

Chemical Properties

3,4-Dimethoxyphenethylamine is clear yellowish oil

Occurrence

3,4-Dimethoxyphenethylamine is a natural product found in Pilosocereus leucocephalus, Vachellia rigidula, and Ototropis elegans with data available.

Uses

3,4-Dimethoxyphenethylamine is a methylated metabolite of Dopamine (D533780); a potent inhibitor of brain mitochondrial respiration used in Parkinson’s disease studies.

Definition

ChEBI: An aromatic ether that is the derivative of 2-phenylethylamine with methoxy substituents at the 3- and 4-positions. It is an alkaloid isolated from the Cactaceae family.

Safety Profile

Poison by intravenous and intraperitoneal routes. When heated to decomposition it emits toxic fumes of NOx.

Purification Methods

Purify the amine by fractionation through an efficient column in an inert atmosphere as it is a relatively strong base. [Horner & Sturm Justus Liebigs Ann Chem 608 12819 1957, Jung et al. J Am Chem Soc 75 4664 1953.] The hydrochloride has m 152o, 154o, 156o (from EtOH, Me2CO or EtOH/Et2O), the picrate has m 165-167o(dec), and the 4-nitrobenzoyl derivative has m 147o [Buck J Am Chem Soc 55 2593 1933]. [Beilstein 13 H 800, 13 IV 2604.]

Global( 629)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
GLR Innovations +91 9891111994 New Delhi, India 4542 58 Inquiry
Danopharm Chemicals Pvt.Ltd. +91 9821080785 Mumbai, India 37 58 Inquiry
SRC Laboratories Pvt Ltd 9676648097 Hyderabad, India 21 58 Inquiry
Vision Drugs Pvt Ltd +91 9948045450 Telangana, India 65 58 Inquiry
Allchem Lifescience Pvt. Ltd +919867655500 Gujarat, India 971 58 Inquiry
CNS CHEMICALS +91-9381957258 +91-9381957258 Telangana, India 354 58 Inquiry
Otto Chemie Pvt Ltd +91-2222070099 +91-2266382599 Maharashtra, India 429 58 Inquiry
Neugen Labs +91-8133254502 +91-8133254502 Karnataka, India 195 58 Inquiry
Adroit Pharmachem Pvt. Ltd. +91-6358748078 +91-6358748078 Gujarat, India 16 58 Inquiry
Integrin Life Sciences. Pvt. Ltd. +91-4040265469 +91-9849990870 Hyderabad, India 90 58 Inquiry
3,4-DiMethoxyphenethylaMine, 98% 100GR 3,4-DiMethoxyphenethylaMine, 98% 25GR NSC 16948 NSC 26152 NSC 6328 3,4-DiMethoxyphenethanaMine 2-(3,4-DIMETHOXYPHENYL)ETHYLAMINE FOR SY 3,4-DiMethoxyphenethylaMine, 97+% Dopamine Impurity C (3,4-Dimethoxyphenethylamine) [D-Met2, Pro5]-Enkephalinamide acetate salt HVTA AURORA KA-7640 B-(3,4-DIMETHOXYPHENYL)ETHYL AMINE BETA-(3,4-DIMETHOXYPHENYL)-ETHYLAMINE RARECHEM AL BW 0210 TIMTEC-BB SBB008220 ,4-Dimethoxypheneethylamine 3,4-dimethoxy-benzeneethanamin 3,4-Dimethoxybenzeneethanamine 3,4-dimethoxy-Benzeneethanamine 3,4-Dimethoxy-beta-phenethylamine 3,4-Dimethoxy-beta-phenylethylamine 3,4-dimethoxydopamine 3,4-dimethoxy-phenethylamin 3,4-Dimethoxyphenylethylamine(base) 3,4-Di-O-methyldopamine 2-(3,4-Dimethoxyphenyl)ethylamine for synthesis Dimethylmescaline Dimpea Dopamine dimethyl ether Homoveratrylamine,4-(-Aminoethyl)veratrole O,O-Dimethyldopamine Phenethylamine, 3,4-dimethoxy- Homoveratrylamin 3,4-DIMETHOXYPHENETHYLAMINE FREE BASE 3,4-DIMETHOXYPHENETHYLAMINE HYDROCHOLORIDE Benzeneethanamine, 3,4-dimethoxy- 3,4-Dimethoxyphenethylamine, Pract. 2-(3,4-Dimethoxyphenyl)ethylamine 96% 2-(3,4-DIMETHOXYPHENYL)ETHYLAMINE / HOMOVERATRYLAMINE 2-(3,4-DIMETHOXYPHENYL)ETHYLAMINE 98+% 3,4-DIMETHOXYPHENETHYLAMINE (HOMOVERATRYLAMINE) 3,4-Dimethoxybenzanamine 1,2-Dimethoxy-4-(2-aminoethyl)benzene 3,4-Dimethoxyphenethylamine,98% 3,4-DiMethoxyphenethyl 2-(3,4-DiMetoxyphenyl)-ethylaMine AKOS 235-24 AKOS NCG1-0105 AKOS BBS-00003591 3,4-DIMETHYLOXYPHENYLETHYLAMINE 3,4-DIMETHOXYPHENETHYLAMINE Benzenethanamine, 3,4-dimethoxy- Dimethoxydopamine 3,4-Dimethoxyphenethylamine,2-(3,4-Dimethoxyphenyl)ethylamine, Homoveratrylamine 3,4-Dimethoxypheneth Dopamine EP Impurity C 3,4-Dimethoxyphenethylamine in stock Factory