tert-butyl(1R,3r,5S)-3-hydroxy-3-methyl-8-azabicyclo[3.2.1]octane-8-carboxylate

tert-butyl(1R,3r,5S)-3-hydroxy-3-methyl-8-azabicyclo[3.2.1]octane-8-carboxylate Structure
CAS No.
870889-86-4
Chemical Name:
tert-butyl(1R,3r,5S)-3-hydroxy-3-methyl-8-azabicyclo[3.2.1]octane-8-carboxylate
Synonyms
SLERKVCWNKEZEG-IWIIMEHWSA-N;endo-8-Boc-3-hydroxy-3-methyl-8-azabicyclo[3.2.1]octane;tert-butyl endo-3-hydroxy-3-methyl-8-azabicyclo[3.2.1]octane-8-carboxylate;tert-butyl(1R,3r,5S)-3-hydroxy-3-methyl-8-azabicyclo[3.2.1]octane-8-carboxylate;3-endo-Hydroxy-3-exo-methyl-8-azabicyclo[3.2.1]octane-8-carboxylic Acid t-Butyl Ester;8-Azabicyclo[3.2.1]octane-8-carboxylic acid, 3-hydroxy-3-methyl-, 1,1-dimethylethyl ester, (3-endo)-
CBNumber:
CB43170775
Molecular Formula:
C13H23NO3
Molecular Weight:
241.32662
MOL File:
870889-86-4.mol

tert-butyl(1R,3r,5S)-3-hydroxy-3-methyl-8-azabicyclo[3.2.1]octane-8-carboxylate Properties

Boiling point 331.2±35.0 °C(Predicted)
Density 1.114±0.06 g/cm3(Predicted)
pka 14.86±0.20(Predicted)

tert-butyl(1R,3r,5S)-3-hydroxy-3-methyl-8-azabicyclo[3.2.1]octane-8-carboxylate Chemical Properties,Uses,Production

Uses

3-endo-Hydroxy-3-exo-methyl-8-azabicyclo[3.2.1]octane-8-carboxylic Acid t-Butyl Ester is an intermediate in the synthesis of ACP-105 (A115650). ACP-105 is a non-steroidal selective androgen receptor modulator used in the treatment of Alzheimer’s.

tert-butyl(1R,3r,5S)-3-hydroxy-3-methyl-8-azabicyclo[3.2.1]octane-8-carboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

tert-butyl(1R,3r,5S)-3-hydroxy-3-methyl-8-azabicyclo[3.2.1]octane-8-carboxylate Suppliers

Global( 3)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
PharmaBlock Sciences (Nanjing), Inc. 4000255188 13327728092 China 9699 58 Inquiry
Jiangsu Aikon Biopharmaceutical R&D Co.,Ltd. 025-66061636 18013972705 China 6763 58 Inquiry
tert-butyl(1R,3r,5S)-3-hydroxy-3-methyl-8-azabicyclo[3.2.1]octane-8-carboxylate SLERKVCWNKEZEG-IWIIMEHWSA-N 3-endo-Hydroxy-3-exo-methyl-8-azabicyclo[3.2.1]octane-8-carboxylic Acid t-Butyl Ester tert-butyl endo-3-hydroxy-3-methyl-8-azabicyclo[3.2.1]octane-8-carboxylate 8-Azabicyclo[3.2.1]octane-8-carboxylic acid, 3-hydroxy-3-methyl-, 1,1-dimethylethyl ester, (3-endo)- endo-8-Boc-3-hydroxy-3-methyl-8-azabicyclo[3.2.1]octane 870889-86-4